ZHNAG yanming

ZHANG Yanming张彦明教授.jpg

Ph.D., Professor

Born in July 1956, Hanzhong City, Shaanxi, China

Contact

Address: College of Veterinary Medicine, Northwest A&F University

No. 22 Xinong Road, Yangling, 712100, Shaanxi, China.

Email: zhangym@nwafu.edu.cn

Mobile: +86 13572931333

Telephone: +86-(0)29-8709-2040

1. Education and Work Experience

12.1998 – now, Professor, College of Veterinary Medicine, Northwest A&F University

12.1994 – 11.1998, Associate Professor, College of Veterinary Medicine, Northwest A&F University

06.1988 – 01.1994, Lecturer, College of Veterinary Medicine, Northwest A&F University

09.1994 – 07.1998, Ph.D., Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University

09.1982 – 07.1985, Master, Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University

09.1978 – 07.1982, Bachelor, Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University

2. Research and Teaching

Research interests:

Prevention and control of epidemic disease in pigs, such as classical swine fever.

Function and regulation of cellular trafficking system in animal RNA virus replication.

Molecular pathogenesis of classical swine fever.

Teaching:

Animal Derived Food Hygiene, Veterinary Public Health for bachelor students.

Veterinary Public Health and Food Safety for master students.

Veterinary Molecular Virology for doctoral students.

3. Memberships and Academic Services

Vice Director, Animal Food Hygiene Branch of Chinese Association of Animal and Veterinary Sciences

Executive Member, Veterinary Public Health Branch of Chinese Association of Animal and Veterinary Sciences

Executive Member, Veterinary Epidemiology Branch of Chinese Association of Animal and Veterinary Sciences

Editor-in-Chief of  Progress in Veterinary Medicine

4. Honors and Awards

Top ten Teachers of Northwest Agricultural University

Lecturing Star Teacher of Northwest A&F University

Third Prize, Prize for Science and Technology Progress in Ningxia Autonomous Region, 2009 (2/28)

5. Publications

Selected papers:

[1] Liang Zhang#, Tao Wang#, Yanyan Yi#, Mengzhao Song, Mingxing Jin, Kangkang Guo*, Yanming Zhang*. ARF1 with Sec7 Domain-Dependent GBF1 Activates Coatomer Protein I To Support Classical Swine Fever Virus Entry.  Journal of virology , 2022, 96(6): e0219321(2022)

[2] Tao Wang, Yaru Liu, Ying Sun, Liang Zhang, Kangkang Guo*, Yanming Zhang*. Rab22a cooperates with Rab5 and NS4B in classical swine fever virus entry process. Veterinary microbiology, 266: 109363. (2022)

[3] Tao Wang#, Liang Zhang#, Wulong Liang#, Shanchuan Liu, Wen Deng, Yangruiyu Liu, Yaru Liu, Mengzhao Song, Kangkang Guo*, Yanming Zhang*.Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.  Autophagy ,https://doi.org/10.1080/15548627.2021.1987673 (2021)

[4] Liang Zhang, Mingxing Jin, Mengzhao Song, Shanchuan Liu, Tao Wang, Kangkang Guo*,Yanming Zhang*. ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.  Veterinary Microbiology , 255:109034 (2021)

[5] Yanfen Jiang, Yinghui Ma, Qianqian Liu, Tianmei Li, Yiming Li, Kangkang Guo*,Yanming Zhang*.Tracing Clostridium perfringens strains from beef processing of slaughter house by pulsed-field gel electrophoresis, and the distribution andtoxinotype of isolates in Shaanxi province, China.  Food Microbiology ,2021:103887 (2021)

[6] Cheng Li, Yifan Wang, Hongqing Zheng, Wang Dong, Huifang Lv, Jihui Lin, Kangkang Guo*and Yanming Zhang*. Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolarmacrophages via inhibition of autophagy by ISGylating BECN1.  Veterinary Research , 2020, 51:22 (2020)

[7] Liang Zhang, Tao Wang, Mengzhao Song, Mingxing Jin, Shanchuan Liu, Kangkang Guo*, Yanming Zhang*. Rab1b-GBF1-ARFs mediated intracellular trafficking is required for classical swine fever virus replication in swine umbilical vein endothelial cells.  Veterinary Microbiology , 246:108743 (2020)

[8] Liang Zhang, Di Zhao, Mingxing Jin, Mengzhao Song, Shanchuan Liu, Kangkang Guo* & Yanming Zhang*. Rab18 binds to classical swine fever virus NS5Aand mediates viral replication and assembly inswine umbilical vein endothelial cells.  Virulence , 11(1):489-501 (2020)

[9] Zhi Cao, Qian Yang, Minping Zheng, Huifang Lv, Kai Kang, Yanming Zhang*. Classical swine fever virus non-structural proteins modulate Toll-likereceptor signaling pathways in porcine monocyte-derived macrophages.  Veterinary Microbiology , 230:101-109 (2019)

[10] Cheng Li#, Hongqing Zheng#, Yifan Wang, Wang Dong, Yaru Liu, Liang Zhang,Yanming Zhang*.Antiviral role of IFITM proteins in Classical swine fever virus infection,  Viruses-Basel , 11(2):126 (2019)

Books:

[1]  Animal Derived Food Hygiene . 6th Edition, Editor-in-Chief, China Agriculture Press (2021).

[2]  Animal Quarantine Technology . 2nd Edition, Editor-in-Chief, China Open University Press (2021)

[3]  Veterinary Public Health . 3rd Edition, Editor-in-Chief, China Agriculture Press (2019)

[4]  Experimental Instruction of Derived Food Hygiene . 2nd Edition, Editor-in-Chief, China Agriculture Press (2015)

[5]  Safety Production and Inspection Technology of Animal Derived Food . Editor-in-Chief, China Agriculture Press (2014)

[6]  Animal Epidemic Prevention and Inspection Iechnology . 2nd Edition, Editor-in-Chief, China Higher Education Press (2011)

[7]  Animal Health and Epidemic Prevention Technology . Editor-in-Chief, China Agriculture Press (2007)

[8]  Inspection Technology of Pollution-Free Food . Editor-in-Chief, China Agriculture Press (2003)

[9]  Diagnostic, Therapeutic and Prevention Techniques of Chicken, Duck and Goose Disease. Editor-in-Chief, China Agriculture Press (2002)

[10]  Therapeutic and Prevention Techniques of   Livestock and Poultry Disease . Editor-in-Chief, Shaanxi Science and Technology Press (1998)

[11]  Guide to Nutrition and Food Hygiene . Editor-in-Chief, Shaanxi Science and Technology Press (1996)

[12]  Zoonotic Diseases . Editor-in-Chief, Northwestern University Press (1994)

6. Projects and Funding

[1] Role and mechanism of coatmer protein Ⅰ on intracellular transport and replication of classical swine fever virus. General Project, No.31772765, National Natural Science Foundation of China (NSFC), 570,000 RMB Yuan, 2017 - 2021, grant holder.

[2] Influence and mechanism of CSFV non-structural proteins on TLRs-mediated innate immune response in swine macrophage. General Project, No.31472210, National Natural Science Foundation of China (NSFC), 880,000 RMB Yuan, 2015 - 2018, grant holder.

[3] Role and mechanism of CSFV NS5A protein in viral pathogenicity. General Project, No.31172339, National Natural Science Foundation of China (NSFC), 600,000 RMB Yuan, 2012 - 2015, grant holder.

[4] Cytopathic effect and molecular mechanism of NS2 protein of Classical swine fever virus. General Project, No. 30972186, National Natural Science Foundation of China (NSFC), 340,000 RMB Yuan, 2010 - 2012, grant holder.

[5] Influence and mechanism of CSFV non-structural proteins on TLRs-mediated innate immune response in swine macrophage. General Project, No. 30771607, National Natural Science Foundation of China (NSFC), 300,000 RMB Yuan, 2008 - 2010, grant holder.

[6] Study on immortalization and expression of E2 gene of Classical swine fever virus in porcine vascular endothelial cells. General Project, No. 30471290, National Natural Science Foundation of China (NSFC), 200,000 RMB Yuan, 2005 - 2007, grant holder.

[7] Study on the specific pathogenic mechanism of Classical swine fever virus to pigs. General Project, No. 30270988, National Natural Science Foundation of China (NSFC), 185,000 RMB Yuan, 2003 - 2005, grant holder.