彭莎

作者:   来源:  发布日期:2016-04-19 浏览次数:

  一、个人基本信息

  彭莎,女,1980年7月,陕西高陵,博士,副研究员,硕士研究生导师,中国生殖生物学会会员,《the Journal of Cytology and Tissue Biology》杂志编委。

  二、教育及研究经历

  教育经历:

  2002年7月毕业于西北农林科技大学畜牧兽医学院临床兽医系临床兽医专业,获学士学位;2007年7月毕业于中国科学院动物研究所生殖生理学专业,获博士学位。

  研究经历:

  2007年7月至2011年12月,西北农林科技大学动物医学院,胰腺干细胞增殖及分化机理,讲师。

  2012年1月至今,西北农林科技大学动物医学院,胰腺干细胞增殖及分化机理,副研究员。

  2012年9月至2013年9月,美国伊利诺伊大学香槟分校,人胚胎干细胞向神经细胞分化的机理研究,访问学者。

  三、研究方向及开设课程

  研究方向:成体干细胞增殖及分化机理。主讲的研究生课程:《蛋白质工程》、《干细胞与组织工程》;主讲的本科生课程:《动物生理学》、《动物生理学实验》、《动物细胞工程》、《动物生物技术概论》。

  四、代表性学术成果(含论著、论文)

  1. Wei Han, Xin He, Mingzhi Zhang, Shuxian Hu, Fen Sun, Lipeng Ren, Jinlian Hua*, Sha Peng S. The establishment of porcine pancreatic stem cell line using T-RExTM system-inducible Wnt3a expression. Cell Proliferation 2015, 48, 301–310.

  2. Xin He, Wei Han, Shuxian Hu, Mingzhi Zhang, Lipeng Ren, Fen Sun, Jinlian Hua*, Sha Peng* . Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine Pancreatic Stem Cells (PSCs). Cell Tissue Research 2015,362(2): 379-388.

  3. Xi Yao, Hao Ren, Wenjing Yang, Thirumalai Diraviyam, Furong Tang, Meng Yu, Jinlian Hua, Xiaoying Zhang*, Sha Peng* “Expression of goat RNA binding protein (NANOS2), development and evaluation of anti-NANOS2 IgY antibodies.” Czech Journal of Animal Science 2015,60 (4): 152-163.

  5. Xi Yao, Furong Tang, Meng Yu, Haijing Zhu, Zhili Chu, Mingzhao Li, Wei Liu*, Jinlian Hua* and Sha Peng* “Expression profi le of Nanos2 gene in dairy goat and its inhibitory effect on Stra8 during meiosis. Cell Proliferation, 2014, 47, 396–405.

  4. Sha Peng*, Wei Han, Xi Yao, Jinlian Hua. Construction and identification of mouse R-spondin 1 eukaryotic expression vector. Journal of Food, Agriculture & Environment 2013,11 (1): 227-230.

  6. Huiru Zhang, Dan Li, Hui Cao,Xiao LV,Yuankui Chu, Yaofu Bai, Yaping Jin, Sha Peng*, Zhongying Dou, Jinlian Hua*. Conophylline promotes the proliferation of immortalized mesenchymal stem cells derived from fetal porcine pancreas (iPMSCs). Journal of Integrative Agriculture 2013, 12(4): 678-686.

  7.Sha Peng, Junlin Zhang, Jiahuan Chen and Huayan Wang “Effects of Wnt5a protein on proliferation and apoptosis in JAR choriocarcinoma cells.” Molecular Medicine Reports 2011, 4: 99-104.

  8. Sha Peng, Jinlian Hua, Xuanhong Cao, Huayan Wang “Gelatin Induces Trophectoderm Differentiation of Mouse Embryonic Stem Cells.” Cell Biology International 2011, 35: 587-591.

  9. Sha Peng, Jing Li, Chenglin Miao, Liwei Jia, Zeng Hu, Ping Zhao, Juxue Li, Ying Zhang, Qi Chen and Enkui Duan  “Dickkopf-1 secreted by decidual cells promotes trophoblast cell invasion during murine placentation”. Reproduction 2008,135:367-375.

  10.Sha Peng,Chenglin Miao,Jing Li,Xiujun Fan,Yujing Cao,Enkui Duan “Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling”. Biochemical and Biophysical Research Communications 2006,350:641-647.

  11. Liming Zheng, Haijing Zhu, Hailong Mu, Jiang Wu, Wencong Song, Yuanxin Zhai, Peng Guangpeng Li, Jinlian Hua. CD49f promotes proliferation of male dairy goat germline stem cells. Cell Proliferation 2016, 49(1): 27-35.

  12.Hui Cao, Yuankui Chu, Xiao Lv, Pubin Qiu, Chao Liu, Huiru Zhang, Dan Li, Sha Peng, Zhongying Dou, Jinlian Hua*.GSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs). PLoS One 2012, 7(2): e31502.

  13.Hui Cao, Yuankui Chu, Haijing Zhu, Junwei Sun, Zhimin Gao , Chunrong Yang, Sha Peng, Zhongying Dou, Jinlian Hua*. Characterization of immortalized mesenchymal stem cells derived from foetal porcine pancreas. Cell Proliferation 2011, 44: 19-32.

  14.Junlin Zhang , Sha Peng, Xiang Cheng, HuayanWang “Functional Analysis of Hybrid Peptide CAMA-Syn: Expression in Mammalian Cells and Antimicrobial Potential.” Protein Peptide Letter. 2012, 19(10):1076-81. (co-first author)

  15.Jiahuan Chen, Zhijuan Lu, De Cheng, Sha Peng, Huayan Wang “Isolation and Characterization of Porcine Amniotic Fluid-Derived Multipotent Stem Cells”. Plos One 2011,6:e19964 (co-corresponding author)

  16.Ying Zhang, Sha Peng, Haibin Kuang, Qi Chen, Shuang Liu, Li Zhang and En-kui Duan. “Expression and regulation of dickkopf2 during periimplantation in mice”. The Journal of Reproduction and Development 2009 55:17-22.

  17.Haibin Kuang, Chenglin Miao, Weixiang Guo, Sha Peng, Yujing Cao, Enkui Duan. “Dickkopf-1 enhances migration of HEK293 cell by beta-catenin/E-cadherin degradation.” Front Bioscience. 2009,14:2212-2220.

  18.Liwei Jia, Jiaxi Zhou, Sha Peng, Jing Li, Yujing Cao, Enkui Duan. “Effects of Wnt3a on proliferation and differentiation of human epidermal stem cells”. Biochemical and Biophysical Research Communications  2008,368:483-488.

  19.Jing Li, Weimin Liu, Yujing Cao, Sha Peng, Ying Zhang, Enkui Duan.  “Roles of Dickkopf-1 and its receptor Kremen1 during embryonic implantation in mice”. Fertility and Sterility 2008,90:1470-1479.

  20.Juxue Li, Chenglin Miao , Weixiang Guo, Liwei Jia , Jiaxi Zhou, Baohua Ma, Sha Peng , Shuang Liu, Yujing Cao, Enkui Duan.“Enrichment of putative human epidermal stem cells based on cell size and collagen type IV adhesiveness”. Cell Research  2008,18:360-371.

  21.Yongjun Yang, Yujing Cao, Shumin Bo, Sha Peng, Weimin Liu, Enkui Duan. “Leptin-directed embryo implantation: Leptin regulates adhesion and outgrowth of mouse blastocysts and receptivity of endometrial epithelial cells”. Animal Reproduction Science 2006,92:155-167.

  22.Yongjun Yang, Weimin Liu, Jiaxi Zhou, Yujing Cao, Jing Li, Sha Peng, Li Wang, Jiang-Gang Yuan, Enkui Duan “Expression and hormonal regulation of calcyclin-binding protein (CacyBP) in the mouse uterus during early pregnancy”. Life Sciences 2006,78:753 -760.

  23. 彭莎,张军林 “稳定表达Wnt3a基因的猪胰腺干细胞株的建立”。农业生物技术学报 2012,20(3): 301-307。

  24. 彭莎,陈家欢,曹选红 “ Wnts 及其相关分子在小鼠外胎盘锥中的表达”。农业生物技术学报 2011,19(2):314-322。

  25. 陈家欢,魏育蕾,彭莎,王华岩 “猪羊水干细胞特异向跳动心肌细胞诱导分化” 生物工程学报 2011, 27(8): 1206−1214。

  26. 华进联,雷安民,彭莎,杨春荣,贺鑫,张仕强,吴江,王龙。《干细胞研究与应用》,中国农业科学技术出版社,2016年2月。

  五、科研项目

  1.教育部留学回国人员启动经费:miR-375在猪PSCs增殖及向胰岛素分泌细胞分化过程中的调控机理,项目编号:K308021501,2015/1-2017/12, 3万,主持。

  2.留学人员科技活动项目择优资助经费:LncRNA对猪PSCs增殖及分化的调控机理,项目编号:Z109021506, 2015/1-2015/12, 2 万,主持。

  3.西北农林科技大学基本科研业务费专项资金项目:miR-375对猪PSC增殖和分化的机理研究,项目编号:Z109021506 2015/1-2015/12,10万,主持。

  4.教育部博士点基金:Wnt/β-catenin在猪PSCs增殖和分化中的作用及机理,项目编号:SRFDP, 20100204120020,2011/1-2012/12,3.6万,主持,结题。

  5.国家自然科学基金:经典Wnt通路在猪PSCs增殖及分化中的作用机理,项目编号:31101775, 2012/1-2014/12,25万元,主持,结题。

  6.08应届博士科研启动费:羊水干细胞分离、培养及向胰岛细胞定向诱导分化的研究, 2008/01-2009/12, 5万元,主持,结题。

  六、荣誉及奖项

  2011年,获得西北农林科技大学青年教师讲课比赛三等奖和动物医学院青年教师讲课比赛一等奖;2010年被评为西北农林科技大学动物医学院“先进个人”;2009-2011年,连续三年被评为西北农林科技大学动物医学院“优秀班主任”。

  七、联系方式

  陕西杨凌邰城路3号西北农林科技大学南校区科研楼,712100,029-87080069,pengshacxh@163.com

 

 


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