MU yang

MU Yang, PhD, Associate Professor穆杨副教授.JPG

Department of Preventative Veterinary Medicine

College of Veterinary Medicine, Northwest A&F University,

Yangling, Shaanxi 712100, P.R. CHINA

Tel: 86-13759872856, 86-29-87091117

Fax: 86-29-87091032

E-mail: muyang@nwafu.edu.cn

lucymu09@yahoo.com

Education

(1) 2001~2006: College of Animal Science and Technology, Northwest A&F University

Graduation: January, 2006

Major: Clinical Veterinary Medicine

Degree: Ph.D

Research Direction: Organismic Pathogen and Immunology

Thesis Topic: Separation and purification of Marek’s disease tumor-associated surface antigen and its monoclonal antibody development

(2) 1998~2001: College of Animal Science and Technology, Northwest A&F University

Graduation: July, 2001

Major: Precautionary Veterinary Medicine

Degree: Master

Research Direction: Molecular Aetiology and Immunology

Thesis Topic: Establish the cultivation of swine vascular endothelial cell  in Vitro  and study on its growth characteristics

(3) 1993~1998:College of Animal Science and Technology, Northwest A&F University

Graduation: July, 1998

Major: Veterinary Medicine

Degree: Bachelor

Professional Experience

(1) Postdoctoral Research

2011/01~2014/06,College of Veterinary Medicine, Northwest A&F University

(2) Visiting scholar

2009/09 - 2010/08,College of Veterinary Medicine, Iowa State University, USA

(3) Associate professor

2009~present: College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi Province, P. R. China

Courses offered: Veterinary immunology; Immunology; Cell and molecule immunology; Experimental technology of immunology, etc.

(4) Lecturer

2004~2008: College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi Province, P. R. China

Courses offered: Veterinary immunology; Essential immunology; Animal immunology; Experimental technology of immunology.

(3) Teaching Assistant

2001~2003: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi Province, P. R. China

Courses offered: Veterinary immunology; Experimental technology of immunology.

Social Part-time

(1) Reviewers of " PLos One ", " International Journal of Biological Sciences ", " Acta Veterinaria et Zootechnica Sinica ", " China Animal Husbandry&Veterinary Medicine ", " Journal of Northwest A&F University (Natural Science Edition) ", " Acta Agriculturae Boreali-occidentalis Sinica ”, and Editorial board member of " Progress in Veterianry Medicine ";

(2) Expert in Dissertation Evaluation of Academic Degree Center of Ministry of Education;

(3) Peer-reviewed experts of NSFC, Natural Science Foundation of Henan Province and Heilongjiang Province, Programs for Science and Technology Development of Henan Province and Heilongjiang Province;

(4) Member of Chinese Society of Immunology

Research field

(1) Pathogenesis of major infectious animal diseases

(2) Molecular etiology and immunology

(3) New technology of disease diagnosis and pathogen detection

(4) Preparation and application of novel antibody

Honor and awards

(1)“Outstanding teacher”, “Outstanding head teacher”, “Prominent individual in college students' ideological and political education”, “Model of academic tutor”, Northwest A&F University, 2019.

(2) “Prominent individual in undergraduate enrollment publicity”, “Prominent Labor Union worker”, “Advanced individual in graduate employment”, 2018.

(3) “Outstanding teacher of 2014 year”, Northwest A&F University. January 25, 2015.

(4) “The second-class award” on the match of prelection for young teachers, Northwest A&F University. December 6, 2014.

In the research project

(1) General project of national Natural Science Foundation of China (31972675),“Mechanism of FGL1/SLAII-LAG3 pathway involved in persistent infection of PRRS”;

(2) Key R&D program of Shaanxi Province (2022NY-099),“Study on Rapid diagnosis of porcine viral reproductive disorders”;

(3) Crosswise tasks from Animal Disease Control and Prevention Center of Shaanxi Province (NYKJ-2018-06),“Research and Demonstration of welfare breeding technology of Dairy Goats based on maintaining immune Function”;

(4) Crosswise tasks from River-Stone Farm (TG2020082), “Comprehensive control and prevention technology of diarrheal diseases in large-scale pig farms”.

Publications

[1] Mu Y*, Jia C, Zheng X, Zhu H, Zhang X, Xu H, Liu B, Zhao Q, Zhou E M*. A nanobody-horseradish peroxidase fusion protein-based competitive ELISA for rapid detection of antibodies against porcine circovirus type 2[J]. J Nanobiotechnology, 2021, 19 (1): 34. (JCR Q1, Zone 1, Top, IF="10.435)"

[2] Zhang X, Zhu H, Zheng X, Jiao Y, Ning L, Zhou E M*, Mu Y*. A Double-Antibody Sandwich ELISA for Sensitive and Specific Detection of Swine Fibrinogen-Like Protein 1[J]. Front Immunol, 2021, 12: 670626.(JCR Q1, Zone 2, Top, IF="7.561)"

[3] Wu X, Fang J, Huang Q, Chen X, Guo Z, Tian L, Zhou E, Chen J, Mu Y*, Du T*. Major Vault Protein Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection in CRL2843(CD163) Cell Lines and Primary Porcine Alveolar Macrophages[J]. Viruses, 2021, 13 (11):2267. (JCR Q2, Zone 2, IF="5.048)"

[4] Hu Y, Zhang X, Wu C, Li X, Mu Y*, Cong R*. Effects of high concentrate diet on expression of inflammatory factors of liver and spleen in dairy goats [J].  Acta Veterinaria et Zootechnica Sinica , 2020, 51(7):1646-1655.

[5] Jiao Y, Zhu H, Zhang X, Wu X, Jia C, Zhou E*, Mu Y*. Establishment of a visual RT-LAMP detection assay for TGEV [J]. Chinese Journal of Veterinary Science, 2020, 40(7): 1272-1279+1285.

[6] Wu X, Fang J, Guo Z, Chen X, Mu Y*, Du T*. Valuation of the role of curcumin on PRRSV infection in piglet[J]. Chinese Journal of Veterinary Science,2020,40(4): 681-685.

[7] Wang L, Zhang L, Huang B, Li K, Hou G, Zhao Q, Wu C, Nan Y, Du T, Mu Y, Lan J, Chen H, Zhou E M. A Nanobody Targeting Viral Nonstructural Protein 9 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication[J]. J Virol, 2019, 93 (4): e01888.

[8] Song L, Han X, Jia C, Zhang X, Jiao Y, Du T, Xiao S, Hiscox J A, Zhou E M*, Mu Y*. Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway[J]. Virol J, 2018, 15 (1): 169. (JCR Q3、Zone 3,IF=2.668):

[9] Song L, Jia C, Han X, Zhou E M*, Mu Y*. The effect of interfering and stable expression of GP5 on the replication of porcine reproductive and respiratory syndrome virus [J].  Acta Veterinaria et Zootechnica Sinica , 2018, 49(6): 1231-1240.

[10] Jia C, Han X, Nie J, Zhang X, Jiao Y, Liu B, Zhou E M*, Mu Y*. Purification of  Camelus Bactrianus serum IgG and preparation and application of its antiserum [J].  Acta Agriculturae Boreali-occidentalis Sinica , 2018, 27 (11): 1584-1590.

[11] Du T, Shi Y, Xiao S, Li N, Zhao Q, Zhang A, Nan Y, Mu Y, Sun Y, Wu C, Zhang H, Zhou E M. Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection[J]. BMC Vet Res, 2017, 13 (1): 298.

[12] Zhang A, Duan H, Li N, Zhao L, Pu F, Huang B, Wu C, Nan Y, Du T, Mu Y, Zhao Q, Sun Y, Zhang G, Hiscox J A, Zhou E M, Xiao S. Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication[J]. Free Radic Biol Med, 2017, 102: 149-161.

[13] Gao J, Xiao S, Xiao Y, Wang X, Zhang C, Zhao Q, Nan Y, Huang B, Liu H, Liu N, Lv J, Du T, Sun Y, Mu Y, Wang G, Syed S F, Zhang G, Hiscox J A, Goodfellow I, Zhou E M. MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection[J]. Sci Rep, 2016, 6: 25120.

[14] Grinnage-Pulley T, Mu Y, Dai L, Zhang Q. Dual Repression of the Multidrug Efflux Pump CmeABC by CosR and CmeR in Campylobacter jejuni[J]. Front Microbiol, 2016, 7: 1097.

[15] Mu Y, Li L L, Zhang B B, Huang B C, Gao J M, Wang X P, Wang C B, Xiao S Q, Zhao Q, Sun Y N, Zhang G P, Hiscox J A, Zhou E M. Glycoprotein 5 of porcine reproductive and respiratory syndrome virus strain SD16 inhibits viral replication and causes G2/M cell cycle arrest, but does not induce cellular apoptosis in Marc-145 cells[J]. Virology, 2015, 484: 136-145.

[16] Li J, Hu L, Liu Y, Huang L, Mu Y, Cai X, Weng C. DDX19A Senses Viral RNA and Mediates NLRP3-Dependent Inflammasome Activation[J]. J Immunol, 2015, 195 (12): 5732-5749.

[17] Xiao S, Wang X, Ni H, Li N, Zhang A, Liu H, Pu F, Xu L, Gao J, Zhao Q, Mu Y, Wang C, Sun Y, Du T, Xu X, Zhang G, Hiscox J A, Goodfellow I G, Zhou E M. MicroRNA miR-24-3p promotes porcine reproductive and respiratory syndrome virus replication through suppression of heme oxygenase-1 expression[J]. J Virol, 2015, 89 (8): 4494-4503.