LIU baoyuan

1. Basic information:刘宝元讲师.jpg

LIU Baoyuan, Ph. D., Lecturer.                                               

2. Education and Work Experiences:

Jun. 2019 - now:  Lecturer, College of Veterinary Medicine, NWAFU, China

Aug. 2017 -Jun. 2019Postdoctor, College of Life Sciences, NWAFU, China

Sep. 2012 -Jun. 2017 Ph. D. (Preventive Veterinary Medicine), College of Veterinary Medicine, NWAFU, China

Sep. 2009 - Jun. 2012 Master (Preventive Veterinary Medicine), College of Veterinary Medicine, Gansu Agricultural University, China

Sep. 2005 - Jun. 2009 Bachelor (Veterinary Medicine), College of Life Science and Engineering, Northwest Minzu University, China

3. Major Research Interests:

Basic research in molecular etiology and immunology, i. e., study on the pathogenicity and cross-species infection of hepatitis E virus; the third generation of genetic engineering antibody (nanobody) has been applied to the novel diagnostic technology and antiviral research of important animal diseases, such as hepatitis E and Porcine circovirus associated diseases.

4. Publications

(1) . Liu BY, Zhou EM, et al. Identification and pathogenicity of hepatitis E Virus from laboratory Bama miniature pigs. BMC Veterinary Research, 2022, 18(1).

(2) . Liu BY, Zhou EM, et al. Identification and pathogenicity of a novel genotype avian hepatitis E virus from silkie fowl (gallus gallus). Veterinary Microbiology, 2020, 245(0).

(3) . Chen YY, Liu BY (corresponding author), Zhou EM, et al. Synthetic Peptides Containing Three Neutralizing Epitopes of Genotype 4 Swine Hepatitis E Virus ORF2 induced Protection against Swine HEV Infection in Rabbit. Vaccines, 2020, 8(2).

(4) . Liu BY, Zhou EM, et al. Experimental infection of rabbit with swine-derived hepatitis E virus genotype 4. Veterinary Microbiology, 2019, 229:168-175.

(5) . Liu BY, Zhou EM, et al. Avian hepatitis E virus infection of duck, goose, and rabbit in northwest China. Emerging microbes & infections, 2018, 7(1):76.

(6) . Chen YY, Liu BY (co-first author), Zhou EM, et al. Characterization of Three Novel Linear Neutralizing B-Cell Epitopes in the Capsid Protein of Swine Hepatitis E Virus. Journal of virology, 2018, 92(13).

(7) . Liu BY, Zhou EM, et al. Effect of housing arrangement on fecal-oral transmission of avian hepatitis E virus in chicken flocks. BMC Veterinary Research, 2017, 13:282.

(8) . Zhao Q, Liu BY (co-first author), Zhou EM, et al. Decreased egg production in laying hens associated with infection with genotype 3 avian hepatitis E virus strain from China. Veterinary Microbiology, 2017, 203:174-180.

(9) . Liu BY, Zhou EM, et al. Rabbit hepatitis E virus is an opportunistic pathogen in specific-pathogen-free rabbits with the capability of cross-species transmission. Veterinary Microbiology, 2017, 201:72-77.

(10). Liu BY, Zhou EM, et al. Development of a blocking ELISA for detection of antibodies against avian hepatitis E virus. Journal of Virological Methods, 2014, 204:1-5.

5. Major research projects:

(1). National Natural Science Foundation of China, Antiviral mechanism of nanobodies against swine, rabbit and avian hepatitis E Virus, 2019-2021, 250,000 RMB Yuan, Program Leader;

(2). China Postdoctoral Science Foundation, Molecular mechanism of host factor CDC42 in the infection of genotype 4 swine hepatitis E virus, 2021-2023, 80,000 RMB Yuan, Program Leader;

(3). Natural Science Foundation of Shaanxi Province, Molecular mechanism and prevention of egg production decline caused by avian hepatitis E virus infection in laying hens, 2020-2021, 50,000 RMB Yuan, project leader;

(4). Chinese Universities Scientific Fund, Study on whole genome amplification and pathogenicity of hepatitis E virus from different animals,  2019-2022, 200,000 RMB Yuan, project leader.

(5) National Natural Science Foundation of China, Mechanism in infection, replication and pathogenicity of animal hepatitis E virus cross-species infection, 2018-2022, 2.3 Million RMB Yuan,  participant.

6. Contact:

ADD: College of Veterinary Medicine, NWAFU, Xinong Road 22, Yangling, 712100, Shaanxi, China

Email: liubaoyuan0412@nwafu.edu.cn

TEL: 15109286126