王兴龙

作者:   来源:  发布日期:2016-04-19 浏览次数:

       一、个人基本信息

  王兴龙,男,山东成武,博士研究生,副教授,硕士生导师。西北农林科技大学动物医学院家畜传染病学主讲教师,动物疫病防控与净化团队骨干成员;国家绒毛用羊细菌病研究室成员;陕西省家兔产业技术体系岗位疫病防控专家;国家自然科学基金委员会生命科学部评议专家。

  二、教育及研究经历

  教育经历:

  2005年6月毕业于南京农业大学动物医学院动物医学专业,获农学学士学位

  2010年6月毕业于南京农业大学动物医学院预防兽医学专业(传染病防治方向),获农学博士学位(硕博连读)

  工作经历:

  2010年7月至2014年12月在西北农林科技大学动物医学院预防兽医系做动物传染病防治研究工作,讲师

  2014年7月至2015年6月在英国爱丁堡大学罗斯林研究所(University of Edinburgh, RoslinInsititue博士后。

  2015年1月至在西北农林科技大学动物医学院预防兽医系做动物传染病防治研究工作,副教授(破格晋升)

  三、科研方向及开设课程

  科研方向:动物传染病防治。

  基础理论研究:猪繁殖与呼吸综合征转录与调控机制研究;

  应用研究:腺病毒载体疫苗开发与利用。

  开设课程:兽医传染病学,猪病学

  四、代表性学术成果

  第一作者论文:

  1.Wang, Xinglong# ,Jia, Yanqing , Wang, Xiangwei , Wang, Chongyang , Lv, Changjie , Li, Xiaoqin , Chu, Zhili , Han, Qingsong , Xiao, Sa , Zhang, Shuxia , Yang, Zengqi. MiR-375 Has Contrasting Effects on Newcastle Disease Virus Growth Depending on the Target Gene. International Journal of Biological Sciences. 2019, 15. 44-57. 10.7150/ijbs.25106.                                              

  2.Xinglong Wang#, Qiuxia Tang#, Li Qiu, ZengqiYang,Penton-dodecahedron of fowl adenovirus serotype 4 as a vaccine candidate for the control of related diseases,Vaccine, 2019,37(6),839-847,                                           

  3.. Wang Xinglong# ;LvChangjie; JiXiaojuan; Wang Bin; Qiu Li; Yang Zengqi ,(*). Ivermectin treatment inhibits the replication of Porcine circovirus 2 (PCV2) in vitro and mitigates the impact of viral infection in piglets. , Virus Research, 2019.263:80~86                                                

  4.. Wang Xinglong #, Dang Ruiyi, Yang Zengqi.  The interferon antagonistic activities of the V proteins of NDV correlated with their virulence. Virus Genes 2019. https://doi.org/10.1007/s11262-019-01637-3                                                                  

  5.Xinglong Wang#, Qiuxia Tang#, Zhili Chu, Peixin Wang, Chen Luo, Yajie Zhang, Xiaoyu Fang, Li Qiu, Ruyi Dang, Zengqi Yang,Immune protection efficacy of FAdV-4 surface proteins fiber-1, fiber-2, hexon and penton base,Virus Research, 245,2018,1-6, https://doi.org/10.1016/j.virusres.2017.12.003.

  6. Wang, Xinglong#, Xiangwei Wang, YanqingJia, Chongyang Wang, Qinsong Han, Zen H. Lu, and Zengqi Yang. "Adenoviral-expressed recombinant granulocyte monocyte colony-stimulating factor (GM-CSF) enhances protective immunity induced by inactivated Newcastle Disease Virus (NDV) vaccine." Antiviral Research, 2017.

  7. Wang, Xinglong#, ShanhuiRen, Xiangwei Wang, Chong Yang Wang, Mengfei Fan, YanqingJia, XiaolongGao, Huan Liu, Sa Xiao, and Zengqi Yang. "Genomic characterization of a wild-bird-origin pigeon paramyxovirus type 1 (PPMV-1) first isolated in the northwest region of China.Archives of virology,2017,162,(3):749-761.      

  8.Xiangwei Wang#, Xinglong Wang#, YanqingJia, Chongyang Wang, Qiuxia Tang, Qingsong Han, Sa Xiao, and Zengqi Yang. Journal of Interferon , Cytokine Research 2017, 37:10, 467-473                       2.419

  9.Wang, Xinglong#, Zhenbing Wang, HongyuXu, Biao Xiang, Ruiyi Dang, and Zengqi Yang. "Orally Administrated Whole Yeast Vaccine Against Porcine Epidemic Diarrhea Virus Induced High Levels of IgA Response in Mice and Piglets." Viral immunology, 2016,29 (9): 526-531.

  10.Wang, Xinglong#, Guohui Mu, Ruiyi Dang, and Zengqi Yang. "Up-regulation of IL-10 upon PRRSV vaccination impacts on the immune response against CSFV." Veterinary microbiology 2016,197: 68-71.          

  11.Wang, Xinglong#, Zhenbin Wang, HongyuXu, Xiang Biao, and Zengqi Yang. "A single amino acid substitution alter antigenicity of Glycosylated protein 4 of HP-PRRSV." Virology journal. 2016,13(1): 129.                         

  12.Wang Xinglong# ,Qui Li, Dang Yu, XiaoSha, Zhang Shuxia, Yang Zengqi(*).Linear Epitope Recognition Antibodies Strongly Respond to the C-terminal Domain of HP-PRRSV GP5 [J]. Veterinary Microbiology, 2014, 174(3-4):565–569.

  13.WangXinglong#, Dang Ruyi, Liu Wenkai, Yang Zengqi(*), Enqi Du, Shuxia Zhang.

  Antigenic characteristics of glycosylated protein 3 of highly pathogenic porcine reproductive and respiratory syndrome virus[J]. Virus research, 2014, 189: 24-28.

  14.WangXinglong#, Wang Jinqiu, HaoHuafang,Qiu Li, Liu Haijing, Chen Shengli, Dang Ruyi, Yang Zengqi(*). Pathogenic Providenciaalcalifaciens Strain that Causes Fatal Hemorrhagic Pneumonia in Piglets[J]. Current microbiology, 2014, 68(3): 278-284.

  15. Wang Xinglong#, HaoHuafang, QiuLi, Dang Ruyi, Du Enqi,ZhangShuxia, Yang Zengqi(*).

  Phylogenetic analysis of rabbit hemorrhagic disease virus in China and the antigenic variation of new strains[J]. Archives of virology, 2012, 157(8): 1523-1530.

  16.Wang Xinglong#, QiuLi, HaoHuafang, Zhang Weidong, Fu Xiangjing, Zhang Hongling, He Shengfang, Zhang Shuxia, Du Enqi, Zengqi Yang(*).  Adenovirus-based oral vaccine for rabbit hemorrhagic disease[J]. Veterinary immunology and immunopathology, 2012, 145(1): 277-282.

  17.WangXinglong#,Junxing Li , JiangPing , LiYufeng,ZeshanBasit, Cao Jun , WangXianwei.. GM-CSF fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus increased the immune responses and protective efficacy against virulent PRRSV challenge. 2009. Virus research. 143. 24-32

  18. Li, Yufeng#, Wang, Xinglong#,Bo Kuntao , WangXianwei , TangBo , YangBaoshou , Jiang Wenming , Jiang Ping. Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China. Veterinary journal. 2007.174. 577-84.

  通讯作者论文:

  1. Xiaoqin Li, YanqingJia, Haijin Liu, Xiangwei Wang, Zhili Chu, Ruochen Hu, Juan Ren, Sa Xiao, Shuxia Zhang, Xinglong Wang*,Zengqi Yang*,High level expression of ISG12(1) promotes cell apoptosis via mitochondrial-dependent pathway and so as to hinder Newcastle disease virus replication, Veterinary Microbiology, 2019, 228,147-156,

  2. Qingsong Han, XiaolongGao, Zhili Chu, Xiangwei Wang, FathalrhmanEisaAddoma Adam, Shuxia Zhang, YanqingJia, XinxinQiu, Xinglong Wang*,Zengqi Yang*,Truncated chicken MDA5 enhances the immune response to inactivated NDV vaccine,Veterinary Immunology and Immunopathology,2019, 208, 44-52,https://doi.org/10.1016/j.vetimm.2018.11.019.

  3.Zhili Chu, Caiying Wang, Qiuxia Tang, Xiaolei Shi, XiaolongGao, Jiangang Ma, Kejia Lu, Qingsong Han, YanqingJia, Xiangwei Wang, FathalrhmanEisaAddoma Adam, Haijin Liu, Sa Xiao,Xinglong Wang*,Zengqi Yang*. Newcastle Disease Virus V Protein Inhibits Cell Apoptosis and Promotes Viral Replication by Targeting CacyBP/SIP. Frontiers in cellular and infection microbiology, 2018; 8: 304.. doi:10.3389/fcimb.2018.00304  3.520

  4. (2) LvChangjie ; Liu Wenkai; Wang Bin; Dang Ruyi; Qiu Li; Ren Juan; Yan Chuanqi; Yang Zengqi *, Wang Xinglong*.Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo , Antiviral Research, 2018.11, 159: 55~62

  5. Ren, Shanhui; Wang, Chongyang; Zhang, Xue; Zhao, Lei; Wang, Xiangwei; Yao, Wei; Han, Qingsong; Wang, Yanhong; Fan, Mengfe; Gao, Xiaolong; Xiao, Sa; Wang, Xinglong*; Yang, Zengqi*. Phylogenetic and pathogenic characterization of a pigeon paramyxovirus type 1 isolate reveals cross-species transmission and potential outbreak risks in the northwest region of China. Archives of Virology, 2017.1-13.              

  6. ShanhuiRen, XiumeiXie, Yanping Wang, Lina Tong, XiaolongGao, YanqingJia, Haixin Wang, Mengfei Fan, Shuxia Zhang, Sa Xiao,Xinglong Wang*, Zengqi Yang*. Molecular characterization of a Class I Newcastle disease virus strain isolated from a pigeon in China." Avian Pathology, 2016,45(4): 408-417.

  7. Wenkai Liu Ruyi Dang ,Xinglong Wang*.Development of a SYBR-based real-time PCR to detect rabbit hemorrhagic disease virus (RHDV) and analyze its tissue distribution in experimentally infected rabbits[J]. VirologicaSinica, 2015, 30(3): 228-230. 

  8.Xiao Li, Li Qiu, Zengqi Yang(*), Ruiyi Dang and Xinglong Wang(*). Emergency vaccination alleviates highly pathogenic porcine reproductive and respiratory syndrome virus infection after contact exposure[J]. BMC veterinary research, 2013, 9(1): 26. 2.

  专利:

  (1) 王兴龙 ,杨增岐,王相伟。一种利用表达GM-CSF的腺病毒提高新城疫灭活疫苗免疫效果的方法及试剂盒, 2016.08.09, 中国, 20160648941.5 (专利)

  五、科研项目

  国家级项目:

  1.十三五重点研发计划子课题:大熊猫与虎重要疫病诊断与检测技术研究。2017.1-2020.12,32万元

  2.国家自然基金青年基金项目面上项目:PRRSV利用多变B-TRS高效转录亚基因组的独特机制研究.2017.1-2020.12, 64万元

  3.国家自然基金青年基金项目:高效转导猪源细胞腺病毒Pt-Dd的筛选及其对猪亚单位疫苗免疫增强作. 2014.1-2016.12,22万元

  省部级项目:

  1.陕西省科技攻关项目:兔出血热病毒的流行病学调查及重组腺病毒疫苗研究.陕西省科技攻关2014.1-2015.12,10万元,结题

  校级及企业项目:

  1.鸽副黏病毒和腺病毒二联疫苗开发和利用,企业合作, 2018.6-2019.6,5万元。

  2.猪重要疫病病原抗原开发和利用,企业合作,2019.1-2019.12,12万元。

  3.中央高校基本科研业务经费:PRRSV 诱导Treg发生分子基础的研究.中央高校基本科研业务经费2011.10-2014.10. 10万元,已结题。

  4.西北农林科技大学人才引进启动项目:高致病性猪繁殖与呼吸综合征重组猪腺病毒口服疫苗研究. 2011.1-2013.12. 5万元,结题。

  六、荣誉和奖项

  2011年教育部科技进步二等奖(排名12)。

  2015年西北农林科技大学青年教师讲课比赛三等奖,西北农林科技大学动物医学院青年教师讲课比赛一等奖。

  2016年动物医学院青年教师讲课比赛二等奖。

  2016、2018年,全国大学生“生泰杯”专业技能大赛优秀培训教师。

  2012、2017、2018年,西北农林科技大学动物医学院考核优秀。

  七、联系方式

  通信地址:陕西杨凌西北农林科技大学动物医学院4307,邮编,712100.

  电子邮箱:wxlong@nwsuaf.edu.cn;93341378@qq.com

  

  寄语:思路决定出路,方向决定未来,欢迎敢想敢干的你一起用拼搏赢得一片天地!


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