黄勇

作者:  来源:  发布日期:2016-05-27 浏览次数:

  一、个人基本信息

  黄勇,男,1975年出生,山西省忻州人,现为西北农林科技大学动物医学院教授、硕士生导师,中国畜牧兽医学会兽医病理学分会理事,陕西省实验动物学会理事,中国微生物学会终生会员,中国免疫学会高级会员,中国生物化学与分子生物学会会员。

  二、教育及研究经历

  1994 年—1999年 天津医科大学临床医学专业获 医学学士 学位2001 年—2004年 第四军医大学生物化学与分子生物学专业获 医学硕士 学位 2004 年—2007年 第四军医大学生物化学与分子生物学专业获 医学博士 学位 2008年—2011年 美国国家食品药物管理局生物制品评价研究中心分子病毒学实验室从事博士后研究工作。

  三、研究方向及开设课程

  研究方向:病原早期快速诊断新技术、感染性疾病的免疫病理机制、免疫抑制型疾病的发病机制

  开设课程:动物病理解剖学、细胞与分子病理学

  四、代表性学术成果

  RuiChao Huo, LiLi Wang, XiaoYa Wang, Yong Zhao, Yi Wang, XiaoMin Zhao, LingLing Chang, SanLu Liu, DeWen Tong, Hai Zhang, Yong Huang. Removal of Regulatory T cells prevents secondary chronic infection but increases the mortality of subsequent sub-acute infection in sepsis mice. Oncotarget. 2016, 7(10):10962-10975. (Correspondence author)

  Qian Du, Yong Huang, TongTong Wang, Xiujuan Zhang, Yu Chen, BaiBai Cui, DeLong Li, XiaoMin Zhao, WenLong Zhang, LingLing Chang, DeWen Tong. Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR. Oncotarget. 2016, 7(14):17492-17507. (Co-First author)

  Hongling Zhang, Yong Huang, Lili Wang, Tingting Yu, Zengguo Wang, Lingling Chang, Xiaomin Zhao, Xiaomao Luo, Liang Zhang, Dewen Tong. Immortalization of porcine placental trophoblast cells through reconstitution of telomerase activity. Theriogenology. 2016;85(8):1446-56. (Co-First author)

  Yong Huang,Na Xing,Zengguo Wang,Xiujuan Zhang,Xiaomin Zhao,Qian Du,Lingling Chang,Dewen Tong, Ultrasensitive Detection of RNA and DNA Viruses Simultaneously Using Duplex UNDP-PCR Assay,PLosOne, 2015,10(11): e0141545

  Yong Huang, Feng Dong, Qian Du, Hongling Zhang, Xiaomao Luo, Xiangjun Song, Xiaomin Zhao, Wenlong Zhang, Dewen Tong. Swainsonine induces apoptosis through mitochondrial pathway and caspase activation in goat trophoblasts. Int J Biol Sci. 2014 Jul 11;10(7):789-97

  Hongling Zhang, Yong Huang, Qian Du, Xiaomao Luo, Liang Zhang, Xiaomin Zhao,Dewen Tong, Porcine parvovirus infection induces apoptosis in PK-15 cells through activation of p53 and mitochondria-mediated pathway .  Biochem Biophys Res Commun, 2015. 456(2): 649-55. (Co-first authors).

  Yong Huang, Xiujuan Zhang, Qian Du, Fengyu Wang, Xaiomin Zhao, Wenlong Zhang, Dewen Tong, Preclinical detection of porcine circovirus type 2 infection using an ultrasensitive nanoparticle DNA probe-based PCR assay, Plos one. 2014, 9(5): e97869.

  Li Ding, Yong Huang, Qian Du, Feng Dong, Xiaomin Zhao, Wenlong Zhang, Xingang Xu, Dewen Tong. TGEV nucleocapsid protein induces cell cycle arrest and apoptosis through activation of p53 signaling. Biochem Biophys Res Commun. 2014, 445(2):497-503(Co-first authors).

  Yong Huang, Li Ding, Zhaocai Li, Meiling Dai, Xiaomin Zhao, Wei Li, Qian Du, Xingang Xu, Dewen Tong. Transmissible gastroenteritis virus infection induces cell apoptosis via activation of p53 signalling. J Gen Virol. 2013, 94:1807-17.

  Yong Huang, Meng Shao, Xingang Xu, Xiujuan Zhang, Qian Du, Xiaomin Zhao, Wenlong Zhang, Yahui Lyu, Dewen Tong. Evidence for different patterns of natural inter-genotype recombination between two PCV2 parental strains in the field. Virus Res. 2013,175(1):78-86.

  Yong Huang, Wei Li, Xiaomin Zhao, Li Ding, Gaoshui Yu, Feng Dong, Qian Du, Xingang Xu, Dewen Tong. Swainsonine differentially affects steroidogenesis and viability in caprine luteal cells in vitro.Theriogenology. 2013 Jul 1;80(1):41-9.

  Feng Dong, Yong Huang, Wei Li, Xiaomin Zhao, Wenlong Zhang, Qian Du, Hongling Zhang, Xiangjun Song, Dewen Tong. The isolation and characterization of a telomerase immortalized goat trophoblast cell line. Placenta, 2013,34(12): 1243–1250. (Co-first authors)

  Li Ding, Yong Huang, Meiling Dai, Xiaomin Zhao, Qian Du, Feng Dong, LiliWang, Ruichao Huo, Wenlong Zhang, Xingang Xu, Dewen Tong. Transmissible gastroenteritis virus infection induces cell cycle arrest at S and G2/M phases via p53-dependent pathway. Virus Res. 2013,178(2):241-51 . (Co-first authors).

  Zhaocai Li, Yong Huang, Feng Dong, Wei Li, Li Ding, GaoShui Yu, Dan Xu, YuanYuan Yang, XinGang Xu, DeWen Tong. Swainsonine promotes apoptosis in human oesophageal squamous cell carcinoma cells in vitro and in vivo through activation of mitochondrial pathway. J Biosci. 2012, 37(6):1005-16. (Co-first authors).

  Yong Huang, YingFeng Lei, Hai Zhang, LiChao Hou, Mingjie Zhang, Andrew Dayton. MicroRNA regulation of STAT4 protein expression: rapid and sensitive modulation of interleukin-12 signaling in human natural killer cells. Blood. 2011,118(26):6793-802.

  Yong Huang, YingFeng Lei, Hai Zhang, Mingjie Zhang, Andrew Dayton. Interleukin-12 treatment down-regulates STAT4 and induces apoptosis with increasing ROS production in human natural killer cell. J Leukoc Biol. 2011, 90:87-97.

  YingFeng Lei, Yong Huang, Hai Zhang, Mingjie Zhang, Andrew Dayton. Functional interaction between cellular P100 and the Dengue virus 3'UTR. J Gen Virol. 2011, 92(Pt 4):796-806. (Co-first authors).

  Yong Huang, YingFeng Lei, Hai Zhang, Mingjie Zhang, Andrew Dayton. Role of interleukin 18 in human natural killer cell is associated with interleukin 2. Mol Immunol, 2010, 47: 2604-10.

  Yong Huang, Ke Dong, Xiaonan Zhang, Bin Zhang, Lichao Hou, Nanchun Chen, Sumin Chen. Expression and regulation of the yggG gene of Escherichia coli. Curr Microbiol. 2008, 56(1):14-20.

  Yong Huang, Bin Zhang,Ke Dong, Xiaonan Zhang,Lichao Hou, Tao Wang, Nanchun Chen, Sumin Chen. Up-regulation of yggG promotes the survival of Escherichia coli cells containing Era-1 mutant protein. FEMS Micro Lett, 2007, 275: 8–15.

  五、科研项目

  1. IL-12诱导的microRNAs对NK细胞功能及脓毒症形成的调控机制,国家自然科学基金,2014-2017。

  2. 畜牧疫病防治关键技术研究,陕西省农业科技创新与攻关,2012-2013。

  3. 利用UNDP-PCR技术早期检测猪腹泻主要病原PEDV和TGEV感染的研究与示范,陕西省农业科技创新与攻关,2015-2016。

  4. 脓毒症形成过程中NK细胞活性变化的分子调控机制研究,西北农林科技大学科技创新重点项目,2013-2015。

  5. 猪重大疫病快速诊断新技术研究,西北农林科技大学国际科技合作基金项目, 2013-2015。

  6. OMP25在布鲁氏菌免疫逃逸中的作用及其调控机制,西北农林大学引进人才科研启动项目, 2011-2014

  7. PCV2诱导猪巨噬细胞高表达IL-10的分子机制,基本科研业务费专项资金项目, 2015.7-2015.12。

  六、联系方式

  地址:陕西杨凌 西北农林科技大学动物医学院

  邮编:712100

  电话:18700906418

  电子邮箱:huangyong@nwsuaf.edu.cn

  


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