马文涛
马文涛,男,博士,副教授。中国免疫学会会员,Clinical Science、Journal of Agricultural and Food Chemistry、BMC Veterinary Research、Bioscience reports等多本SCI杂志审稿人。为本科生开设《兽医免疫学》和《免疫学》课程,为全校研究生开设《免疫学原理与技术》、《细胞与分子免疫学》、《兽医生物制品研发的理论与实践》等课程。研究方向主要为山羊重大疫病的免疫防治,研究内容主要包括流行病调查与病原分离鉴定、病原相关分子及免疫分子的单克隆抗体研制、检测试剂盒与疫苗开发、机体抗感染免疫机制研究、动物肠道菌群研究及益生菌制剂开发等。先后主持国家自然科学基金(青年项目)、青海省重点研发与转化项目、陕西省自然科学基础研究计划等多项科研项目。截至目前(2021年6月前)以第一或通讯作者身份发表SCI论文22篇(其中影响因子3分以上论文15篇),中文核心期刊论文7篇。指导学生参加第五届全国大学生生命科学创新创业大赛,获二等奖。带领学生针对青海省绵羊养殖业中的疫病防控问题开展对口支援帮扶工作,团队获得陕西省大学生暑期社会实践扶贫攻坚专项活动先进团队称号,本人被评为2019年陕西省社会实践活动先进个人。
二、教育及工作经历
主要学习经历:
2011年6月毕业于西北农林科技大学,动物医学院,动物医学专业,获农学学士学位;
2017年6月毕业于中国科学技术大学,生命科学学院,细胞生物学专业,获理学博士学位;
主要工作经历:
2017年6月--2020年12月,西北农林科技大学动物医学院,讲师。
2021年1月--至今,西北农林科技大学动物医学院,副教授。
三、代表性学术论文(截至2021年6月前)
Cheng Hongyu, Li Weijuan, Li Xingming, Fan Qinlei, Tang Xidian, Liu Mingjie, Ma Wentao*, Chen Dekun*, Pathogenicity of blood orf virus isolates in the development of dairy goat contagious pustular dermatitis. Veterinary Microbiology, 2018(219):178-82.(兽医学Top期刊,影响因子="3.03)
Ma Wentao#*, Gu Kui#, Yang Rui, Qi Yuxu, Liu Mingjie, Chen Dekun*, Interleukin-17 mediates lung injury by promoting neutrophil accumulation during the development of contagious caprine pleuropneumonia. Veterinary Microbiology, 2020(243):108651.(兽医学Top期刊,影响因子="3.03" )
Tong Juanzhen#, Ma Wentao#, Yang Rui, Wang Tianxing, Chen Xi, Zhang Xinyue, Tang Xidian, Wen Ying, Chang Jianjun*, Chen Dekun*, Dysbiosis of the gut microbiota maybe exacerbate orf pathology by promoting inflammatory immune responses, Veterinary Microbiology, 2020(251):108884. (兽医学Top期刊,影响因子="3.03" )
Tang Xidian, Jing Tian, Chen Xi, Wang Tianxing, XieYanfei, Chen Fengqiang, Wen Ying, Chang Jianjun, Chen Dekun*, Ma Wentao*, Interleukin-17 mediates inflammatory tissue injury during orf development in goats, Veterinary Microbiology 258 (2021) 109105. (兽医学Top期刊,影响因子="3.03" )
Pang Ming, Guan Xiong, ZuoChenxiang, Liu Mingjie, Saad Rehman, Fan Qinlei, Lu Ping, Chen Dekun, Ma Wentao*. Development of a Monoclonal Antibody to Detect αs1-casein in the Milk of Healthy and Mastitis-Affected Goats, KafkasUniversitesiVeterinerFakultesiDergisi, 2019(26):71-74. (本科生发表,影响因子="0.489)
Ni Silu, Gao Fei, ZuoChenxiang, Tang Xidian, Liu Mingjie, Chang Jianjun, Wang Yong, Chen Dekun Chen, Ma Wentao*, Neutrophils: A Critical Participator in Common Diseases of Ruminants, KafkasUniversitesiVeterinerFakultesiDergisi, 2020,26(5): 719-727. (本科生发表,影响因子="0.489)
Ma Wentao#, Liu Qi#, Ning Mengxia, Qi Yuxu, Saad Rehman, Chen Denkun*, Development and applications of a monoclonal antibody against caprine interferon-gamma, BMC Biotechnology, 2019(19). (影响因子="2.312)
Gao Yang, Sang Fengfeng, Meng Delan, Wang Yi, Ma Wentao*, Chen Dekun*, Preparation of a novel monoclonal antibody against caprine interleukin-17A and its applications in immunofluorescence and immunohistochemistry assays, BMC Biotechnology, 2019 (19):47. (影响因子="2.312)
Ma Wentao, Wang Yi, Gao Fei, Ning Mengxia, Liu Ahua, Li Yanyan, Gao Yang, Lu Ping, Chen Dekun*, Development of a Monoclonal Antibody against Bovine α-casein to Evaluate Functional Status of Mammary Epithelial Cells During Mastitis, KafkasUniversitesiVeterinerFakultesiDergisi, 2019(25):445-450. (影响因子="0.489)
Yao Xiaoting, Pang Ming, Wang Tianxing, Chen Xi, Tang Xidian, Chang Jianjun, Chen Dekun*, Ma Wentao*. Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades, Pathogens, 2020, 9(11), 888. (影响因子="3.02)
Chang Jianjun#*, Yao Xiaoting#, ZuoChenxiang, Qi Yuxu, Chen Dekun*, Ma Wentao*, The gut bacterial diversity of sheep associated with different breeds in Qinghai province, BMC Veterinary Research, 2020,16(1):254. (影响因子= 1.835)
ZhannurNiyazbekova, Yao Xiaoting, Liu MingJie, Bold Nomin, Tong Juanzhen, Chang Jianjun, Wen Ying, Li Li, Wang Yong, Chen Dekun*, Ma Wentao*. Compositional and Functional Comparisons of the Microbiota in the Colostrum and Mature Milk of Dairy Goats, Animals, 2020, 10(11): 1955. (影响因子="2.32)
Hong-Yu Cheng, Meng-Xia Ning, De-Kun Chen*, Wen-Tao Ma*, Interactions between the gut microbiota and the host innate immune response against pathogens, Frontiers in Immunology, 2019(10):607. (影响因子="5.085)
Mingjie Liu, Saad Rehman, Xidian Tang, Kui Gu, Qinlei Fan, Dekun Chen* and Wentao Ma*, Methodologies for Improving HDR Efficiency, Frontiers in Genetics. 2019; 9:691. (影响因子="3.258)
Hongyu Cheng, Xiong Guan, Dekun Chen* and Wentao Ma*, The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story, Microorganisms, 2019(7). Doi: 10.3390/microorganisms7120583. (影响因子="4.152).
Ma Wentao*, Yao Xiaoting, Peng Qun, ChenDekun*.The protective and pathogenic roles of IL-17 in viral infections: friend or foe? Open Biology, 2019. (影响因子="4.931)
Tang Xidian, Gao Fei, Liu Mingjie, Fan Qinlei, Chen Dekun*, Ma Wentao*, Methods for Enhancing Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Homology-Directed Repair Efficiency, Frontiers in Genetics, 2019(10):551. Doi: 10.3389/fgene.2019.00551. (影响因子="3.258)
Ma Wentao*, Gao Fei, Gu Kui, Chen Dekun*, The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review, Frontiers in Immunology, 2019 (10):1140. (影响因子="5.085)
Ma Wentao*, Chen Dekun*, Immunological Abnormalities in Patients with Primary Biliary Cholangitis, Clinical Science, 2019(133):741-760. (影响因子="5.223)
Wen-Tao Ma, Christopher Chang, M Eric Gershwin*, Zhe-Xiong Lian*, Development of autoantibodies precedes clinical manifestations of autoimmune diseases: A comprehensive review, Journal of Autoimmunity , 2017(83):95-112. (影响因子="6.658)
Wen-Tao Ma#, Yan-Jie Jia#, Qing-Zhi Liu, et al., Modulation of liver regeneration via myeloid PTEN deficiency, Cell Death & Disease, 2017(5):e2827(影响因子="6.304)
Wen-Tao Ma#, Qing-Zhi Liu#, Jing-Bo Yang, et al., A mouse model of autoimmune cholangitis via syngeneic bile duct protein immunization, Scientific Reports, 2017(1):15246. (影响因子="3.998)
Hong-Di Ma, Wen-Tao Ma, Qing-Zhi Liu, Zhi-Bin Zhao, Mu-Zi-Ying Liu, Koichi Tsuneyama, Jin-Ming Gao, William M. Ridgway, Aftab A. Ansari, M. Eric Gershwin, Yun-Yun Fei and Zhe-Xiong Lian, Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8+ T cell activation, Journal of Autoimmunity2017;78:19-28.(影响因子="6.658)
Shasha Zhu, Jiqian Zhang, Li Zhang,Wen-Tao Ma, Na Man, Yiming Liu, Wei Zhou, Jun Lin, Pengfei Wei, PeipeiJin, Yunjiao Zhang, Yi Hu, Erwei Gu, Xianfu Lu, Zhilai Yang, Xuesheng Liu, Li Bai andLongping Wen,Inhibition of Kupffer Cell Autophagy Abrogates Nanoparticle-Induced Liver Injury,Advanced Healthcare Materials2017;6(9)(影响因子="7.367)
五、科研项目
国家自然科学基金青年项目,γδT细胞介导新生羔羊传染性脓疱皮炎免疫病理损伤的机制研究,24万元,2020-2022,主持。
青海省重点研发与转化项目,肠益菌群增强藏绵羊抗病力的技术创新集成与示范推广,20万元,2021-2023,主持。
陕西省自然科学基础研究计划,提升奶山羊免疫力的关键有益菌群筛选与鉴定,3万元,2020-2021,主持。
校企合作项目,青海省湟中上新庄白石头肉羊养殖基地绵羊主要疫病发病情况调查及防控措施制定,2万元,2020-2021,主持。
西北农林科技大学博士科研启动项目,Th17细胞在奶山羊乳腺炎发病过程中的作用机制探究,20万元,2017-2019,主持。
青海省重点研发与转化项目,青海绵羊规模化养殖中主要疫病防控关键技术集成示范与推广,200万元,2018-2021,主要参与人。
青海省农牧厅科技项目,青海省绵羊养殖中羊口疮疫病防控与免疫技术研究,10万元,2018-2019,主要参与人。
陕西省重点产业创新链(群)项目,奶山羊原料奶及羊奶粉中牛乳成分的快速精确检测技术研究与示范,50万元,2018-2020,主要参与人。
六、联系方式
通讯地址:陕西,杨凌,西北农林科技大学,动物医学院。邮编:712100。
Email: mawentao@nwafu.edu.cn