王娟
一、个人基本信息
姓名：王娟 性别：女
职称：副教授 学位：博士
所在系：预防兽医系 导师类型：博导兼硕导
政治面貌：无党派人士 出生年月：1983.10
籍贯：山东省德州市
电子邮箱：juan.wang1234@hotmail.com; juan.wang@nwafu.edu.cn
二、个人简介
目前主要致力于细菌致病及耐药机制研究，近年来，运用基因组学等技术深入解析了大肠杆菌、沙门氏菌、肺炎克雷伯菌、产气荚膜梭菌、伪结核棒状杆菌、支原体等病原菌致病的分子机制，解析了相关耐药基因的遗传环境，阐明了其传播流行扩散的分子机制。主持国家自然科学基金及省部级课题10余项；以第一作者或通讯作者（含共同）发表论文20余篇；担任Journal of Antimicrobial Chemotherapy、Antimicrobial Agents and Chemotherapy、Microbial Drug Resistance、Microbiology Spectrum、Frontiers in Microbiology等多家主流SCI期刊特约审稿专家。2021年至今，委任陕西省病原微生物实验室生物安全专家委员会委员，中国畜牧兽医学会动物微生态学分会第六届理事，陕西省预防医学会第二届病原微生物检验专业委员会委员；2023年1月起委任为陕西省现代农业产业技术体系-生物安全技术体系动物源细菌耐药性监测与控制岗位专家和陕西省科协评审专家；2023年10月起委任为陕西省预防医学会病原微生物检验专业委员会第二届委员会副主任委员。 2024年4月起委任第二届全国兽药残留与耐药性控制专家委员会委员。2024年6月起委任《中国抗生素杂志》第二届青年编委委员。现为国家自然科学基金委员会生命科学部同行评议专家、教育部学位中心论文评审专家。
三、教育及工作经历
教育经历：
2003年9月-2008年6月，滨州医学院，临床医学专业，获学士学位
2008年9月-2011年6月，西安交通大学，微生物与免疫专业，获硕士学位，师从 徐纪茹教授
2011年9月-2015年6月，爱尔兰都柏林大学，公共卫生与人口健康学院，食品安全风险评估重点实验室，获博士学位，师从 Séamus Fanning教授
工作经历：
2014年9月-2015年9月，爱尔兰都柏林大学，公共卫生与人口健康学院，食品安全风险评估重点实验室，博士后
2015年10月-2017年12月，西北农林科技大学，动物医学院预防兽医系，讲师
2018年1月至今，西北农林科技大学，动物医学院预防兽医系，副教授
四、教学工作
本科生课程：《兽医微生物学》、《兽医传染病学》、《兽医流行病学》
研究生课程：《动物疫病防控与案例分析》、《动物传染病学进展》、《动物流行病学进展》
五、研究领域
One Health
动物源食品安全
细菌耐药性
细菌致病性
兽用生物制品
六、科研项目
（1）国家自然科学基金面上项目：新型optrA阳性质粒在产气荚膜梭菌中的富集与传播机制，2025/01-2028/12
（2）国家重点研发计划:“动物疫病综合防控关键技术研发与应用”重点专项，禽重要疫病新型诊断技术与产品研发，课题4“鉴别诊断技术与产品研发”，课题骨干，2024-2027
（3）横向课题：浙江汇能生物股份有限公司，那西肽对羊源产气荚膜梭菌临床分离株的药敏试验，项目主持人，2023/07-2024/07
（4）卫生部食品安全风险评估重点实验室开放课题：产气荚膜梭菌中optrA阳性质粒在食品、动物及人群之间的传播风险研究，项目主持人，2023/06-2024/06
（5）陕西省重点研发计划国际科技合作计划项目：“一带一路”倡议下中巴两国规模鸡场重要病原菌耐药性传播机制及防控技术研究，项目主持人，2021/01-2023/12
（6）宁夏回族自治区重点研发计划项目：畜禽养殖场兽用抗菌药使用减量化关键技术应用研究；项目参与人，2021/01-2023/12
（7）国家重点研发计划:“食品微生物检验相关参考物质体系研究与评价”项目（2017YFC1601400）课题2“食源性微生物耐药参考物质体系研究与评价”，课题编号2017YFC1601402, 课题骨干，2018-2022
（8）国家自然科学基金青年基金项目：nik基因影响mcr-1基因表达和传播的作用及机制研究，项目主持人，26万元，2018/01-2020/12
（9）陕西省博士后特别资助：多粘菌素耐药基因播散机制的研究，项目主持人，15万元，2017/02-2018/11
（10）中国博士后科学基金第十一批特别资助：松弛酶基因影响 mcr-1 基因表达和传播的机制研究，项目主持人，15万元，2018/04-2019/10
（11）中国博士后科学基金第六十一批面上项目：质粒编码ESBLs类基因传播分子机制及其适应性代价研究，项目主持人，5万元，2017/02-2018/11
（12）中央高校基本科研业务费：9万元，2017/05-2020/04
（13）陕西省引进博士资助经费：20万元，2018/04-2021/03
（14）西北农林科技大学博士科研启动经费：猪源性多重耐药质粒的产生及跨种属传播机制，20万元，2016/01-2018/12
七、专利申请：
申请(专利)号：CN202210891805.4
申请日期：2022-07-27
公开/公告日期：2022-11-01
申请(专利权)人：西北农林科技大学
发明人：杨增岐，魏宇辰，王斌，王晨骁，王娟，白新栋
（2）一种用微管检测布鲁菌病的方法
申请(专利)号：202310463069
申请(专利权)人：西北农林科技大学
发明人：王兴龙，刘一鸣，王娟，冶冬阳
（3）一种D型产气荚膜梭菌21-D-5、外毒素、疫苗及制备方法和应用
申请号：202410723791.4
发文序号：2024060501309320
申请日：2024年06月05日
申请人：西北农林科技大学
发明人：杨增岐，王娟，张域琪，韩宇，王兴龙，冶冬阳，窦磊娜，冯航
八、历年发表文章
2024年：
1. Ke Wu#, Juan Wang#, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin*, Rong Zhang*, Hongning Wang*. Genomic adaptation of Clostridium perfringens to human intestine. 2024. iMetaOmics. （Accepted）
2. Mingjin Fang, Yuan Yuan, Edward M. Fox, Ke Wu, Xin Tian, Likun Zhang, Hang Feng, Ruichao Li, Li Bai, Xinglong Wang, Zengqi Yang*, Rong Zhang, Juan Wang*. Prevalence and genomic characteristics of becAB-carrying Clostridium perfringens strains. Food Microbiology, Volume 125, 2025, 104640, ISSN 0740-0020, https://doi.org/10.1016/j.fm.2024.104640. Food Microbiology.
3. Ke Wu, Yuan Yuan, Mingjin Fang, Yiwen Liu, Danjiao Yang, Likun Zhang, Xin Tian, Leina Dou, Dongyang Ye, Edward M. Fox, Juan Wang* and Zengqi Yang*. Genomic insights into cpb2-positive Clostridium perfringens and the potential biological function of cpb2 gene. One Health Advances.
4. Ruiwei Wang , Xuhong Cao , Kejia Lu , Zhengwu Chang , Xiaoyu Dong , Hanwei Guo , Xi Wei , Ruyi Dang , Juan Wang, Xinglong Wang , Sa Xiao , Haijin Liu and Zengqi Yang * . Rescuing Newcastle disease virus with tag for screening viral-host interacting proteins based on highly efficient reverse genetics. Frontiers in Veterinary Science, 2024. DOI 10.3389/fvets.2024.1418760.
5. Hang Feng1, Ke Wu1, Yuan Yuan, Mingjin Fang, Juan Wang**, Ruichao Li, Rong Zhang, Xinglong Wang, Dongyang Ye*, Zengqi Yang*. Genomic analysis of Clostridium perfringens type D isolates from goat farms. Veterinary Microbiology, 2024. https://doi.org/10.1016/j.vetmic.2024.110105. (共同通讯作者，五年IF=3.5，TOP期刊，中科院农林科学2区，兽医学1区)
6. Biao Tang#, Haoyu Zhao#, Jie Li#, Na Liu, Yuting Huang, Juan Wang*, Min Yue*. Detection of clinical Serratia marcescens isolates carrying blaKPC-2 in a hospital in China. HELIYON, 2024. https://doi.org/10.1016/j.heliyon.2024.e29702. (共同通讯作者，五年IF=4.1，综合性期刊3区)
7. Xueliang Zhao*, Yongqiang Miao*, Hongmei Chen, Honghu Shan, Juan Wang, Yang Wang, Jianzhong Shen#, Zengqi Yang#. Identification of a novel multi-drug resistant plasmid co-harbouring Extended-Spectrum β-Lactamase resistance genes blaPER-4 and blaOXA-10 in Moellerella wisconsensis of sheep. Journal of Integrative Agriculture, 2024. https://doi.org/10.1016/j.jia.2024.03.040. (五年IF=4.8，农林科学1区，G4)
8. Yuhua Zhang#, Zheng Lu#, Haoyu Zhao#, Shuangyu Li#, Hong Zhuang#, Juan Wang, Ruichao Li, Weibo Zheng, Hongwei Zhu, Peng Xie, Yibin Hu, Caiyuan Zhou, Qian Mao, Leilei Sun, Shanshan Li, Wenhui Wang, Fang Wang, Wei Pan*, Chengbao Wang*. Antimicrobial resistance and genomic characterization of Salmonella isolated from Pigeons in China, Transboundary and Emerging Diseases (跨界和新兴疾病), 2024, (五年IF=4.3，农林科学2区，G3)
9. Shuangyu Li#, Xinshuai Liu#, Haoyu Zhao#, Yuhua Zhang#, Zheng Lu#, Juan Wang, Ruichao Li, Peng Xie, Yibin Hu, Caiyuan Zhou, Qian Mao, Leilei Sun, Shanshan Li, Wenhui Wang, Fang Wang, Xinyu Liu, Tiantian Liu, Wei Pan*, Chengbao Wang*. Genome-Based Molecular Diversity of Extended-Spectrum β-Lactamase-Producing Escherichia coli From Pigeons in China. Transboundary and Emerging Diseases, 2024, 1828830, 11 pages, 2024. https://doi.org/10.1155/2024/1828830.
10. Yu Han, Chongyang Wang, Chongsheng Bai, Enying Diao, Binxuan Yuan, Kejia Lu, Xiaoyu Dong, Riteng Zhang, Bin Han, Haijin Liu, Juan Wang, Xinglong Wang, Sa Xiao, Zengqi Yang. Bovine parainfluenza virus type 3 infections induce ER stress-mediated autophagy to facilitate virus replication, Veterinary Microbiology, 2024, 110051, ISSN 0378-1135. (五年IF=3.5，TOP期刊，中科院农林科学2区，兽医学1区，G3)
11. 潘瑶#，杨丹娇#，袁媛#，方明锦，吴建平，田维，肖海月，王娟*，蓝岚*。牛结节性皮肤病研究进展。动物医学进展，2024。
12. 吴克，王娟*，杨增岐*。动物源产气荚膜梭菌致病因子和耐药性研究进展，中国兽医杂志，2024,60(3):84-89。DOI:10.20157/j.cnki.zgsyzz.2024.03.013.
13. 袁媛，吴克, 张雯, 崔生玲, 杨奇, 杨丹娇, 杨文欢, 冯航, 方明锦, 田欣, 王兴龙, 王娟*, 杨增岐*。陕西省、甘肃省和宁夏回族自治区羊源D型产气荚膜梭菌特征分析，中国兽医学报, 2024。
14. 张域琪，王娟，韩蕾，黎璞，马文涛，张春，李雅丽，袁晶，雷金娥。三株致肝脓肿高毒力肺炎克雷伯菌的生物学特性及基因特征分析。西安交通大学学报（医学版），2024。（已接收）
2023年：
15. Ke Wu, Zhe Li, Mingjin Fang, Yuan Yuan, Edward M Fox, Yingqiu Liu, Ruichao Li, Li Bai, Wen Zhang, Wei-Min Zhang, Qi Yang, Lingling Chang, Pu Li, Xinglong Wang , Juan Wang*, Zengqi Yang*. Genome characteristics of the optrA-positive Clostridium perfringens strain QHY-2 carrying a novel plasmid type. mSystems. 2023 Aug 31;8(4):e0053523. doi: 10.1128/msystems.00535-23. （通讯作者，五年IF=7.3，中科院生物学2区）
16. Yongqiang Miao, Xueliang Zhao, Jianlin Lei, Jingru Ding, Hang Feng, Ke Wu, Jiaohu Liu, Chunyang Wang, Dongyang Ye, Xinglong Wang, Juan Wang, Zengqi Yang*. Characterization of Lung Microbiomes in Pneumonic Hu Sheep Using Culture Technique and 16S rRNA Gene Sequencing. Animals (Basel). 2023 Aug 30;13(17):2763. doi: 10.3390/ani13172763.（IF=3.0/Q1，中科院农林科学2区）
17. Yongqiang Miao, Xueliang Zhao, Fathalrhman Eisa Addoma Adam, Qingfang Xie, Hang Feng, Jingru Ding, Xindong Bai, Juan Wang*, Zengqi Yang*. Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China: A Case Report. Microorganisms. 2023 Jan 29;11(2):333. doi: 10.3390/microorganisms11020333.（通讯作者，五年IF=4.8，中科院生物学2区）
18. Chunyang Wang, Honghu Shan, Hui Chen, Xindong Bai, Jingru Ding, Dongyang Ye, Fathalrhman Eisa Addoma Adam, Yawei Yang, Juan Wang*, Zengqi Yang*. Probiotics and vitamins modulate the cecal microbiota of laying hens submitted to induced molting. Frontiers in Microbiology. 2023 May 9;14:1180838. doi: 10.3389/fmicb.2023.1180838. （通讯作者，五年IF=6.2，TOP期刊，中科院生物学2区）
19. Xiaoyu Lu, Pei Zhang, Pengcheng Du, Xiuli Zhang, Juan Wang, Yingying Yang, Honghu Sun, Zhiqiang Wang, Shenghui Cui, Ruichao Li, Li Bai. Prevalence and Genomic Characteristics of mcr-Positive Escherichia coli Strains Isolated from Humans, Pigs, and Foods in China. Microbiology Spectrum. 2023 Apr 12:e0456922. doi: 10.1128/spectrum.04569-22. （五年IF=5.9，TOP期刊，中科院生物学1区）
20. Yanyun Gao, Pengcheng Du, Pei Zhang, Juan Wang, Ziyi Liu, Séamus Fanning, Zhiqiang Wang, Ruichao Li, Li Bai. Dynamic evolution and transmission of a blaNDM-1-bearing fusion plasmid in a clinical Escherichia coli. Microbiological Research. 2023 Oct;275:127450. doi: 10.1016/j.micres.2023.127450. （五年IF=7.1，中科院生物学2区）
21. Zhengwu Chang, Xiaoyu Dong, Zhao Guan, Kejia Lu, Xi Chen, Xi Wei, Hanwei Guo, Ruyi Dang, Juan Wang, Xinglong Wang, Sa Xiao, Zengqi Yang, Haijin Liu. Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China. Veterinary Microbiology. 2023 Sep 8;285:109872. doi: 10.1016/j.vetmic.2023.109872. （五年IF=3.5，TOP期刊，中科院农林科学2区）
22. Jiangang Ma, Juan Wang, Hua Yang, Mengru Su, Ruichao Li, Li Bai, Jie Feng, Yuting Huang, Zengqi Yang, Biao Tang. IncHI1 plasmids mediated the tet(X4) gene spread in Enterobacteriaceae in porcine. Frontiers in Microbiology. 2023 Mar 30:14:1128905. doi: 10.3389/fmicb.2023.1128905. (共同一作，五年IF=6.2，TOP期刊，中科院生物学2区)
23. 叶超,张域琪,吴克,王娟*. 噁唑烷酮/酰胺醇类耐药基因optrA研究进展.国外医药抗生素杂志.已接收.
24. 赵浩宇, 赵学亮, 张域琪, 吴滨滨, 闫振达, 董晓宇, 杨增岐, 王娟, 党如意.朱鹮源大肠埃希氏菌分离鉴定及耐药性与致病性研究[J].动物医学进展, 2023, 44(4):134-138.
25. 张域琪, 杨增岐, 王娟. 携带噁唑烷酮耐药基因optrA藏羊源产气荚膜梭菌的检测[J].动物医学进展, 2023, 44(3):128-131.
26. 张域琪, 吴克, 赵浩宇, 吴滨滨，李颖，杨增岐，王兴龙，王娟. 关中奶山羊铜绿假单胞菌的分离鉴定及其耐药性与毒力基因的检测[J].中国兽医科学, 2023.
27. 吴滨滨，冯航，刘英, 张域琪, 丁敬茹, 王娟*, 杨增岐*.圈养朱鹮源大肠埃希菌的耐药性、毒力基因、及种系分型检测分析[J].动物医学进展，2023.
2022年：
28. Xueliang Zhao, Yongqiang Miao, Fathalrhman Eisa Addoma Adam, Haoyu Zhao, Zilian Zhou, Mengru Su, Ruichao Li, Baowei Yang, Zexun Lv, Sa Xiao, Xinglong Wang, Juan Wang, Zengqi Yang. ESBLs-producing Escherichia coli from sheep-origin: Genome-wide virulence genes identification and in vivo virulence assessment in mice and Galleria mellonella. Transbound Emerg Dis. 2022 Nov;69(6):3606-3617. doi: 10.1111/tbed.14729. （通讯作者，五年IF=4.3，中科院农林科学2区）
29. Ke Wu#, Juan Wang#, Hang Feng, Ruichao Li，Xinglong Wang and Zengqi Yang*. Complete genome sequence and characterization of Clostridium perfringens type D carrying optrA-plasmid and Tn6218-like transposon. Journal of Antimicrobial Chemotherapy. 2022 Dec 23;78(1):311-313. doi: 10.1093/jac/dkac393. PMID: 36411256.（共同第一作者，五年IF=5.4，TOP期刊，中科院医学2区）
30. Chongyang Wang#, Ruochen Hu#, Liuyuan Duan, Qili Hou, Mengqing Yang, Ting Wang, Haijin Liu, Sa Xiao, Ruyi Dang, Juan Wang, Xinglong Wang, Shuxia Zhang *, Zengqi Yang *. The canonical Wnt/β-catenin signaling pathway facilitates pseudorabies virus proliferation and enhances virus-induced autophagy. Veterinary Microbiology.2022 Sep;272:109502. doi: 10.1016/j.vetmic.2022.109502. Epub 2022 Jul 11. PMID: 35841697. （五年IF=3.5，TOP期刊，中科院农林科学2区）
31. Xueliang Zhao, Haoyu Zhao, Zilian Zhou, Yongqiang Miao, Ruichao Li, Baowei Yang, Chenyang Cao, Sa Xiao, Xinglong Wang, Haijin Liu, Juan Wang*, Zengqi Yang*. Characterization of Extended-Spectrum b-Lactamase-Producing Escherichia coli Isolates That Cause Diarrhea in Sheep in Northwest China. Microbiology Spectrum. 2022. Aug 31;10(4):e0159522. doi: 10.1128/spectrum.01595-22. Epub 2022 Aug 9. PMID: 35943154; PMCID: PMC9431196. （通讯作者，五年IF=5.9，TOP期刊，中科院生物学1区）
32. Ke Wu, Hang Feng, Jiangang Ma, Bin Wang, Jie Feng, Hui Zhang, Yanfen Jiang, Ruichao Li, Juan Wang* and Zengqi Yang*. Prevalence, toxin-typing and antimicrobial susceptibility of Clostridium perfringens in sheep with different feeding modes from Gansu and Qinghai provinces, China. Anaerobe. 2022 Feb;73:102516. doi: 10.1016/j.anaerobe.2022.102516. Epub 2022 Jan 10. PMID: 35026419. （通讯作者，TOP期刊，中科院生物学3区）
33. Chongyang Wang#, Ting Wang#, Liuyuan Duan, Hui Chen, Ruochen Hu, Xiangwei Wang, Yanqing Jia, Zhili Chu, Haijin Liu, Xinglong Wang, Shuxia Zhang, Sa Xiao, Juan Wang, Ruyi Dang*, Zengqi Yang*. Evasion of Host Antiviral Innate Immunity by Paramyxovirus Accessory Proteins. Frontiers in Microbiology. 2022 Jan 31;12:790191. doi: 10.3389/fmicb.2021.790191. PMID: 35173691; PMCID: PMC8841848. (TOP期刊，中科院生物学2区)
34. Jie Feng, Mengru Su, Kun Li, Jiangang Ma, Ruichao Li, Li Bai, Xinglong Wang*, Juan Wang* and Zengqi Yang*. Extensive spread of tet(X4) in multidrug-resistant Escherichia coli of animal origin in western China. Veterinary Microbiology. 2022 Jun;269:109420. doi: 10.1016/j.vetmic.2022.109420. Epub 2022 Apr 4. PMID: 35533579. (通讯作者，TOP期刊，中科院农林科学2区)
35. Biao Tang, Jingge Wang, Xue Zheng, Jiang Chang, Jiangang Ma, Juan Wang, Xiaofeng Ji, Hua Yang, Baoan Ding. Antimicrobial resistance surveillance of Escherichia coli from chickens in the Qinghai Plateau of China. Frontiers in Microbiology. 2022 Jul 22;13:885132. doi: 10.3389/fmicb.2022.885132. PMID: 35935206; PMCID: PMC9354467. (TOP期刊，中科院生物学2区)
36. Peixin Wang, Xin Ma, Riteng Zhang, Yongxin Zhao, Ruochen Hu, Chen Luo, Basit Zeshan, Zengqi Yang, Li Qiu, Juan Wang, Haijin Liu, Yefei Zhou, Xinglong Wang.The transcriptional characteristics of NADC34-like PRRSV in porcine alveolar macrophages. Frontiers in Microbiology. 2022 Oct 19;13:1022481. doi: 10.3389/fmicb.2022.1022481. PMID: 36338035; PMCID: PMC9629508.(TOP期刊，中科院生物学2区)
37. Miao Yongqiang, Zhao Xueliang, Adam FEA, Xie Qingfang, Feng Hang, Ding Jingru, Bai Xindong, Wang Juan*, Yang Zengqi*. Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China. Microorganisms. 2023; 11(2):333. https://doi.org/10.3390/microorganisms11020333 （通讯作者，中科院微生物学3区）
38. Yuan Tian, Liting Wu, Rui Lu, Hongduo Bao, Yan Zhou, Maoda Pang, Joseph Brown, Juan Wang, Ran Wang, Hui Zhang. Virulent phage vB_CpeP_HN02 inhibits Clostridium perfringens on the surface of the chicken meat. International Journal of Food Microbiology, Volume 363, 16 February 2022, 109514.（TOP期刊，中科院农林科学1区）
39. 吴克,冯航,王娟,党如意*,杨增岐*.动物源产气荚膜梭菌的流行率与耐药性分析[J].国外医药(抗生素分册),2022,43(01):37-41.DOI:10.13461/j.cnki.wna.005436.
40. 吴克,冯航,王斌,王晨骁,王娟*,杨增岐*.一起D型产气荚膜梭菌引起小规模关中奶山羊腹泻报道[J].中国兽医学报,2022,42(09):1856-1860.DOI:10.16303/j.cnki.1005-4545.2022.09.20.
41. 吴克,冯航,王娟*,杨增岐*.关中奶山羊源D型产气荚膜梭菌全基因组序列测定及其分子特征分析[J].畜牧兽医学报,2022,53(11):3967-3974.
42. 白新栋,王斌,王晨骁,王小园,王娟,刘海金,杨增岐*,党如意*.天鹅维氏气单胞菌、弗氏柠檬酸杆菌与大肠埃希氏菌混合感染的诊断[J].动物医学进展,2022,43(06):139-144.DOI:10.16437/j.cnki.1007-5038.2022.06.024.
43. 白新栋,王晨骁,王斌,吴克,王小园,王娟,党如意*,杨增岐*.羊源生物2型犬巴氏杆菌的分离鉴定及药敏试验[J].动物医学进展,2022,43(03):24-27.DOI:10.16437/j.cnki.1007-5038.2022.03.018.
44. 赵学亮,王斌,苗永强,赵浩宇,谢青芳,王娟*,杨增岐*.陕西地区羊源致病性大肠杆菌耐药性分析与毒力基因检测[J].畜牧兽医学报,2022,53(05):1644-1648.
45. 王晨骁,王斌,冯航,吴克,王娟,杨增岐*.羊溶血性曼氏杆菌的分离鉴定及药敏试验[J].动物医学进展,2022,43(02):90-94.DOI:10.16437/j.cnki.1007-5038.2022.02.010.
2021年：
46. Jie Feng#, Qian Xiang#, Jiangang Ma, Pei Zhang, Kun Li, Ke Wu, Mengru Su, Ruichao Li, Daniel Hurley, Li Bai, Juan Wang* and Zengqi Yang*. Characterization of Carbapenem-Resistant Enterobacteriaceae Cultured From Retail Meat Products, Patients, and Porcine Excrement in China. Frontiers in Microbiology. 2021 Dec 23;12:743468. doi: 10.3389/fmicb.2021.743468. eCollection 2021.（通讯作者，TOP期刊，中科院生物学2区）
47. Xueliang Zhao, Yunyang Lv, Fathalrhman Eisa Addoma Adam, Qingfang Xie, Bin Wang, Xindong Bai, Xiaoyuan Wang, Honghu Shan, Xinglong Wang, Haijin Liu, Ruyi Dang*, Juan Wang* and Zengqi Yang*. Comparison of Antimicrobial Resistance, Virulence Genes, Phylogroups, and Biofilm Formation of Escherichia coli Isolated From Intensive Farming and Free-Range Sheep. Frontiers in Microbiology. 2021 Jul 30;12:699927. doi: 10.3389/fmicb.2021.699927. eCollection 2021.（通讯作者，TOP期刊，中科院生物学2区）
48. Zengyuan Liu#, Yingqiu Liu#, Wei Xi, Shuangshi Liu, Jia Liu, Hailong Mu, Beibei Chen, Hao He, Yunpeng Fan, Wuren Ma, Weimin Zhang, Mingzhe Fu, Juan Wang* and Xiaoping Song*. Genetic Features of Plasmid- and Chromosome-Mediated mcr-1 in Escherichia coli Isolates From Animal Organs With Lesions. Frontiers in Microbiology. 2021 Aug 5;12:707332. doi: 10.3389/fmicb.2021.707332. eCollection 2021. （通讯作者，TOP期刊，中科院生物学2区）
49. Chongyang Wang†, Ting Wang†, Jiangkun Dai, Zhiyuan An, Ruochen Hu, Liuyuan Duan, Hui Chen, Xiangwei Wang, Zhili Chu, Haijin Liu, Juan Wang, Na Li*, Zengqi Yang* and Junru Wang*.1-Formyl-β-carboline Derivatives Block Newcastle Disease Virus Proliferation through Suppressing Viral Adsorption and Entry Processes. Biomolecules. 2021 Nov 12;11(11):1687. doi: 10.3390/biom11111687. PMID: 34827684; PMCID: PMC8616010.（中科院生物学2区）
50. Pengcheng Du, Pei Zhang, Juan Wang, Ruichao Li, Séamus Fanning, Li Bai*. Molecular characterization of two novel NDM-1-producing atypical enteroaggregative Escherichia coli isolates from patients. Plasmid. 2021 May;115:102568. doi: 10.1016/j.plasmid.2021.102568. Epub 2021 Feb 23. PMID: 33636219.（中科院生物学3区）
51. Wei Li, Yanfei Yan, Jia Chen, Ruiwen Sun, Yuxuan Wang, Tingfen Wang, Zitian Feng, Kai Peng, Juan Wang, Sheng Chen, Yanping Luo, Ruichao Li*, Baowei Yang *. Genomic characterization of conjugative plasmids carrying the mcr-1 gene in foodborne and clinical strains of Salmonella and Escherichia coli.Food Control.（TOP期刊，中科院农林科学1区）
52. 张琳慧,苏梦茹,王卓,王娟*.mcr基因介导的多黏菌素耐药机制研究进展[J].动物医学进展,2022,43(03):99-102.DOI:10.16437/j.cnki.1007-5038.2022.03.012.
53. 苏梦茹,叶超,赵学亮,冯航,王娟*,杨增岐.猪源肠外致病性大肠埃希氏菌的分离鉴定与药敏试验[J].动物医学进展,2022,43(07):124-128.DOI:10.16437/j.cnki.1007-5038.2022.07.015
54. 吴克,冯航,白新栋,陈林千雨,王娟*,杨增岐*.1株牛源致病性蜡样芽孢杆菌特征分析[J].中国兽医学报,2022,42(03):472-476.DOI:10.16303/j.cnki.1005-4545.2022.03.10.
55. 吴克,冯航,白新栋,陈林千雨,王娟*,杨增岐*.1株牛源致病性蜡样芽孢杆菌特征分析[J].中国兽医学报,2022,42(03):472-476.DOI:10.16303/j.cnki.1005-4545.2022.03.10.
56. 赵学亮,李哲,王晨骁,王娟,王兴龙,党如意*,杨增岐*.林麝源大肠埃希菌的分离、鉴定及耐药性与致病性分析[J].中国兽医学报,2021,41(10):1970-1975.DOI:10.16303/j.cnki.1005-4545.2021.10.14.
2020年：
57. Jiangang Ma#, Juan Wang#, Jie Feng, Yingqiu Liu, Baowei Yang, Ruichao Li, Li Bai, Tao He, Xinglong Wang*, Zengqi Yang*. Characterization of three porcine Acinetobacter towneri strains co-harboring tet(X3) and blaOXA-58. Frontiers in Cellular and Infection Microbiology. 2020 Dec 10;10:586507. doi: 10.3389/fcimb.2020.586507. eCollection 2020. (共同第一作者，中科院2区)
58. Pei Zhang#, Juan Wang#, Xinglong Wang, Xue Bai, Jiangang Ma, Ruyi Dang, Yifei Xiong, Séamus Fanning, Li Bai* and Zengqi Yang*. Characterization of Five Escherichia coli Isolates Co-expressing ESBL and MCR-1 Resistance Mechanisms From Different Origins in China. Frontiers in Microbiology. 2019 Aug 29;10:1994. doi: 10.3389/fmicb.2019.01994. eCollection 2019. (共同第一作者，TOP期刊，中科院2区)
59. 赵学亮, 王晨骁, 王斌, 冯航，叶超，党如意，王娟，杨增岐. 羊源D型产气荚膜梭菌分离鉴定及耐药性与致病性分析[J]. 中国兽医学报, 2021, 41(7):5.
2019年：
60. Ruichao Li, Pei Zhang, Xiaorong Yang, Zhiqiang Wang, Séamus Fanning, Juan Wang, Pengcheng Du and Li Bai*. Identification of a novel hybrid plasmid coproducing MCR-1 and MCR-3 variants from an Escherichia coli strain. Journal of Antimicrobial Chemotherapy.2019 Jun 1;74(6):1517-1520. doi: 10.1093/jac/dkz058. PMID: 30793748.（TOP期刊，中科院医学2区）
2017年：
61. Juan Wang, Min Yuan, Hai Chen, Xia Chen, Yuanchun Jia, Xiong Zhu, Li Bai, Xue Bai, Séamus Fanning, Jinxing Lu, Juan Li*. First Report of Klebsiella Oxytoca Strain Simultaneously Producing NDM-1, IMP-4 and KPC-2 Carbapenemases. Antimicrobial Agents and Chemotherapy. 2017 Aug 24;61(9):e00877-17. doi: 10.1128/AAC.00877-17. PMID: 28674063; PMCID: PMC5571352. (TOP期刊，中科院医学2区)
62. Juan Wang, Xianglei Li, Juan Li, Daniel Hurley, Xue Bai, Zhongyi Yu, Yu Cao, Ellen Wall, Séamus Fanning*, Li Bai*. Complete Genetic Analysis of A Salmonella Enterica Serovar Indiana Isolate Accompanying Four Plasmids Carrying mcr-1, ESBL and Other Resistance Genes in China. Veterinary Microbiology.2017 Oct;210:142-146. doi: 10.1016/j.vetmic.2017.08.024. Epub 2017 Sep 14. PMID: 29103683.（TOP期刊，中科院农林科学2区）
63. Li Bai#, Juan Wang#, Daniel Hurley, Zhongyi Yu, Lili Wang, Qian Chen, Juan Li, Fengqin Li and Séamus Fanning*. A novel disrupted mcr-1 gene and a lysogenized phage P-1 like sequence, cultured from a human atypical enteropathogenic Eschrichia coli (aEPEC) recovered in China. Journal of Antimicrobial Chemotherapy. 2017 May 1;72(5):1531-1533. doi: 10.1093/jac/dkw564. PMID: 28088770.（TOP期刊，中科院医学2区）
64. Li Bai, Lili Wang, Xiaorong Yang, Juan Wang, Xin Gan, Wei Wang, Jin Xu, Qian Chen, Ruiting Lan, Séamus Fanning and Fengqin Li*. Prevalence and molecular characteristics of extended-spectrum β-lactamase genes in Escherichia coli isolated from diarrheic patients in China. Frontiers in Microbiology. 2017 Feb 13;8:144. doi: 10.3389/fmicb.2017.00144. PMID: 28243225; PMCID: PMC5303722.(TOP期刊，中科院生物学2区)
2016年：
65. Juan Wang, James Gibbons, Kathleen McGrath, Li Bai, Fengqin Li, Finola C. Leonard, Roger Stephan and Séamus Fanning*. Molecular characterization of blaESBL-producing Escherichia coli cultured from pig farms in Ireland. Journal of Antimicrobial Chemotherapy. 2016 Nov;71(11):3062-3065. doi: 10.1093/jac/dkw278. Epub 2016 Jul 25. PMID: 27494914.（TOP期刊，中科院医学2区）
66. Juan Wang, Daniel Hurley, Kathleen McGrath, Li Bai, Herbert Hachler, Roger Stephan and Séamus Fanning*. Draft genome sequence of Escherichia coli 26R 793, a plasmid-free recipient strain commonly used in conjugation assays. Genome Announcement.2016 Oct 20;4(5):e00707-16. doi: 10.1128/genomeA.00707-16. PMID: 27795232; PMCID: PMC5073249.(在线开放期刊)
67. Evan Brennan, Marta Martins, Matthew P. McCusker, Juan Wang, Bruno Martins Alves, Daniel Hurley, Farid El Garch, Frederique Woehrle, Christin Miossec, Leisha McGrath, Shabarinath Srikumar, Patrick Wall and Séamus Fanning*. Multidrug-resistant Escherichia coli in bovine animals, Europe. Emerging Infectious Diseases. 2016 Sep;22(9):1650-2. doi: 10.3201/eid2209.160140. PMID: 27533105; PMCID: PMC4994333. (TOP期刊，中科院医学2区，影响因子：16.12)
68. Li Bai, Daniel Hurley, Juan Li, Qiong Meng, Juan Wang, Séamus Fanning and Yanwen Xiong*. Characterisation of multidrug-resistant Shiga toxin-producing Escherichia coli cultured from pigs in China: co-occurrence of extended-spectrum β-lactamase- and mcr-1-encoding genes on plasmids. International Journal of Antimicrobial Agents. 2016 Oct;48(4):445-8. doi: 10.1016/j.ijantimicag.2016.06.021. Epub 2016 Aug 1. PMID: 27526978. (中科院医学2期)
69. Li Bai, Jiayong Zhao, Xin Gan, Juan Wang, Xiuli Zhang, Shenghui Cui, Shengli Xia, Yujie Hu, Shaofei Yan, Jiahui Wang, Fengqin Li, Séamus Fanning and Jin Xu*. Emergence and diversity of Salmonella enterica serovar Indiana isolates with concurrent resistance to ciprofloxacin and cefotaxime from patients and food-producing animals in China. Antimicrobial Agents and Chemotherapy.2016 May 23;60(6):3365-71. doi: 10.1128/AAC.02849-15. PMID: 27001808; PMCID: PMC4879380.(TOP期刊，中科院医学2区)
2015年：
70. Qiongqiong Yan, Juan Wang, Jayanthi Gangiredla, Yu Cao, Marta Martins, Gopal Gopinath, Roger Stephan, Keith Lampel, Ben Tall and Séamus Fanning*. Comparative genotypic and phenotypic analysis of Cronobacter species cultured from four powdered infant formula production facilities: indication of pathoadaptation along the food chain. Applied and Environmental Microbiology.2015 Jul;81(13):4388-402. doi: 10.1128/AEM.00359-15. Epub 2015 Apr 24. PMID: 25911470; PMCID: PMC4475896. (TOP期刊，中科院生物学2区)
71. Darren Carroll, Juan Wang, Séamus Fanning and Barry McMahon*. Antimicrobial resistance in wildlife: implications for public health. Zoonoses and Public Health.2015 Nov;62(7):534-42. doi: 10.1111/zph.12182. Epub 2015 Feb 2. PMID: 25639901. (TOP期刊，中科院农林科学2区)
72. Muhammad Nawaz, Chaofeng Ma, MAR Basra, Juan Wang, Jiru Xu*. Amelioration of ovalbumin induced allergic symptoms in Balb/c mice by potentially probiotic strains of lactobacilli. Beneficial Microbes.2015;6(5):669-78. doi: 10.3920/BM2014.0141. Epub 2015 Apr 22. PMID: 25869278. (医学4区)
73. Katrin Zurfluh, Karen Power, Jochen Klumpp, Juan Wang, Séamus Fanning and Roger Stephan*. A novel Tn3-like composite transposon harbouring blaVIM-1 in Klebsiella pneumonia spp. pneumonia isolated from river water. Microbial Drug Resistance.2015 Feb;21(1):43-9. doi: 10.1089/mdr.2014.0055. Epub 2014 Aug 6. PMID: 25098892. (医学4区)
74. Juan Wang, Roger Stephan, Katrin Zurfluh, Herbert Hächler and Séamus Fanning*. Characterization of the genetic environment of blaESBL genes, integrons and toxin-antitoxin systems identified on large transferrable plasmids in multi-drug resistant Escherichia coli. Frontiers in Microbiology. 2015 Jan 6;5:716. doi: 10.3389/fmicb.2014.00716. PMID: 25610429; PMCID: PMC4285173.(TOP期刊，中科院生物学2区)
2014年：
75. Juan Wang, Roger Stephan, Karen Power, Qiongqiong Yan, Herbert Hächler and Séamus Fanning*. Nucleotide sequences of 16 transmissible plasmids identified in nine multidrug-resistant Escherichia coli isolates expressing an ESBL phenotype isolated from food-producing animals and healthy humans. Journal of Antimicrobial Chemotherapy.2014 Oct;69(10):2658-68. doi: 10.1093/jac/dku206. Epub 2014 Jun 11. PMID: 24920651.（TOP期刊，中科院医学2区）
76. Karen Power#, Juan Wang#, Maria Karczmarczyk, Brenden Crowley, Meaghan Cotter, Pippa Haughton, Maureen Lynch, Kirsten Schaffer and Séamus Fanning*. Molecular analysis of OXA-48-carrying conjugative IncL/M-like plasmids in clinical isolates of Klebsiella pneumoniae in Ireland. Microbial Drug Resistance.2014 Oct;69(10):2658-68. doi: 10.1093/jac/dku206. Epub 2014 Jun 11. PMID: 24920651. (医学4区)
77. Maria Karczmarczyk#, Juan Wang#, Nola Leonard and Séamus Fanning*. Complete nucleotide sequence of a conjugative IncF plasmid from an Escherichia coli isolate of equine origin containing blaCMY-2 within a novel genetic context. FEMS Microbiology Letters. 2014 Mar;352(1):123-7. doi: 10.1111/1574-6968.12364. Epub 2014 Jan 6.
78. Katrin Zurfluh, Juan Wang, Jochen Klumpp, Magdalena Nuesch-Inderbinen, Séamus Fanning and Roger Stephan*. Vertical transmission of highly similar blaCTX-M-1-harbouring IncI1 plasmids in Escherichia coli with different MLST types in the poultry production pyramid. Frontiers in Microbiology. 2014 Sep 30;5:519. doi: 10.3389/fmicb.2014.00519. PMID: 25324838; PMCID: PMC4179741. (TOP期刊，中科院生物学2区)
79. Ash Burns, Bryan Markey, Anna Shore, Marie Galligan, Julia Sabirova, James Gibbons, David Coleman, Malhotra Surbhi, John Egan, Séamus Fanning, Juan Wang and Nola Leonard*. A longitudinal study of Staphylococcus aureus colonization in pigs in Ireland. Veterinary Microbiology. 2014 Dec 5;174(3-4):504-513. doi: 10.1016/j.vetmic.2014.10.009. Epub 2014 Oct 25. PMID: 25465665.（TOP期刊，中科院农林科学2区）
2013年：
80. Juan Wang, Roger Stephan, Maria Karczmarczyk, Qiongqiong Yan, Herbert Hächler and Séamus Fanning*. Molecular characterization of blaESBL-harboring conjugative plasmids identified in multi-drug resistant Escherichia coli isolated from food-producing animals and healthy humans. Frontiers in Microbiology. 2013 Jul 11;4:188. doi: 10.3389/fmicb.2013.00188. PMID: 23874325; PMCID: PMC3708134. (TOP期刊，中科院生物学2区)
2011年：
81. Muhammad Nawaz, Juan Wang, Aiping Zhou, Chaofeng Ma, Xiaokang Wu, John E Moore, B Cherie Millar, Jiru Xu. Characterization and transfer of antibiotic resistance in lactic acid bacteria from fermented food products. Curr Microbiol. 2011 Mar;62(3):1081-9. doi: 10.1007/s00284-010-9856-2.
82. 周爱萍, 韩蕾, 王娟, 段艳, 吴晓康, 徐纪茹. 结核杆菌DnaA蛋白的原核表达及免疫血清的制备和检测. 西安交通大学学报(医学版). 2011,32(01): 50-53+88.
2010年：
83. Xiaokang Wu, Chaofeng Ma, Lei Han, Muhammad Nawaz, Fei Gao, Xuyan Zhang, Pengbo Yu, Chang'an Zhao, Lianchuan Li, Aiping Zhou, Juan Wang, John E Moore, B Cherie Millar, Jiru Xu. Molecular characterisation of the faecal microbiota in patients with type II diabetes. Curr Microbiol. 2010 Jul;61(1):69-78. doi: 10.1007/s00284-010-9582-9. Epub 2010 Jan 20. PMID: 20087741.
84. 吴晓康, 徐纪茹, 张旭燕, 马超锋, 韩蕾, 申艳星, NAWAZ M, 王娟. 2型糖尿病患者肠道拟类菌属和双歧杆菌属多样性的PCR-DGGE指纹图谱分析. 西安交通大学学报(医学版). 2010,31(04): 475-480.
导师寄语： 路虽远行则将至，事虽难做则必成。
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（读博士期间的碎碎念，现在已经没有时间更新了，留作回忆了哈。^_^）
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