杜谦
一、个人基本信息
杜谦，汉族，籍贯湖北仙桃，博士，副教授，硕士生导师，中国畜牧兽医学会动物病理学分会会员，陕西省实验动物学会会员。
二、教育及工作经历
2005年9月—2009年6月 西北农林科技大学 动物医学专业 获农学学士学位；
2009年9月—2016年6月 西北农林科技大学 基础兽医学专业 获农学博士学位；
2016年8月—2022年9月 西北农林科技大学动物医学院 讲师；
2022年10月—至今 西北农林科技大学动物医学院 副教授。
三、研究方向及主讲课程
动物病理学，主要从事猪圆环病毒2型致病和复制机制研究。
主要讲授《动物病理学》、《动物病理解剖学》等课程。
四、代表性论文
1. Qian Du#, Xuefeng Yang#, Mengyu Ma, Qi Zhang, Changlei Zhu, Tengfei Shi, Mingrui He, Dewen Tong*, Yong Huang*. The gC1qR binding site mutant PCV2 is a potential vaccine strain that does not impair memory CD4+ T-cell generation by vaccines. Journal of Virology. 2022. 96(19): e0095922.
2. Qian Du#, Tengfei Shi#, Huaxin Wang, Changlei Zhu, Nan Yang, Dewen Tong*, Yong Huang*. The ultrasonically treated nanoliposomes containing PCV2 DNA vaccine expressing gC1qR binding site mutant Cap is efficient in mice. Frontiers in Microbiology. 2023. 13: 1077026.
3. Qian Du, Xuezhi Zhang, Ning Xu, Mengyu Ma, Bichen Miao, Huang Yong*, Tong Dewen*. Chaperonin CCT5 binding with porcine parvovirus NS1 promotes the interaction of NS1 and COPƐ to facilitate viral replication. Veterinary Microbiology. 2022. 274: 109574.
4. Qian Du#, Huan Zhang#, Mingrui He, Xuan Zhao, Jia He, Beibei Cui, Xuefeng Yang, Dewen Tong*, Yong Huang*. Interleukin-10 promotes porcine circovirus type 2 persistent infection in mice and aggravates the tissue lesions by suppression of T cell infiltration. Frontiers in Microbiology. 2019. 10: 2050.
5. Qian Du#, Xingchen Wu#, Tongtong Wang#, Xuefeng Yang, Zhenyu Wang, Yingying Niu, Xiaomin Zhao, Shan-Lu Liu, Dewen Tong*, Yong Huang*. Porcine circovirus type 2 suppresses il-12p40 induction via Capsid/gC1qR-mediated microRNAs and signalings. The Journal of Immunology. 2018. 201(2): 533-547.
6. Xiaohua Zhang#, Qian Du#, Guiyuan Chen, Yiyuan Jiang, Kai Huang, Linghao Li, Dewen Tong*, Yong Huang*. Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments. Veterinary Research. 2023. 54(1): 21.
7. Cong Han#, Qian Du#, Lei Zhu, Nannan Chen, Le Luo, Qiao Chen, Jiatong Yin, Xingchen Wu, Dewen Tong*, Yong Huang*. Porcine DNAJB6 promotes PCV2 replication via enhancing the formation of autophagy in host cells. Veterinary Research. 2020. 51(1): 61.
8. Tongtong Wang#, Qian Du#, Yingying Niu, Xiaohua Zhang, Zhenyu Wang, Xingchen Wu, XueFeng Yang, Xiaomin Zhao, Shan-Lu Liu, Dewen Tong*, Yong Huang*. Cellular p32 is a critical regulator of porcine circovirus type 2 nuclear egress. Journal of Virology. 2019. 93(23): e00979-19.
9. Tongtong Wang#, Qian Du#, Xingchen Wu, Yingying Niu, Lijuan Guan, Zhenyu Wang, Xiaomin Zhao, Shan-Lu Liu, Dewen Tong*, Yong Huang*. Porcine MKRN1 modulates the replication and pathogenesis of PCV2 by inducing capsid protein ubiquitination and degradation. Journal of Virology.2018. 92(11): e00100-18.
10. Delong Li#, Qian Du#, Bin Wu, Juejun Li, Lingling Chang, Xiaomin Zhao, Yong Huang, Dewen Tong*. Immunogenicity of adenovirus vaccines expressing the PCV2 capsid protein in pigs. Vaccine. 2017. 35(36): 4722-4729.
11. Dan Xu#, Qian Du#, Cong Han, Zengguo Wang, Xiujuan Zhang, Tongtong Wang, Xiaomin Zhao, Yong Huang, Dewen Tong*. p53 signaling modulation of cell cycle arrest and viral replication in porcine circovirus type 2 infection cells. Veterinary Research. 2016. 47(1): 120-131.
12. 袁玮艺, 黄凯, 原宇, 郑芳芳, 唐耀松, 林小枫, 童德文*, 杜谦*. 一起雏鸭大肠埃希氏菌感染病例的诊断. 动物医学进展. 2022. 43(12): 140-144.
13. 林小枫, 刘梅雪, 袁玮艺, 张琼歌, 朱磊, 杜谦*. 生物素标记重组猪圆环病毒2d基因型毒株感染性克隆的构建与鉴定. 中国兽医杂志. 2022. 58(05): 16-21+28.
14. 杜谦, 杨楠, 史腾飞, 朱磊, 黄勇*, 童德文*. 3种猪自然细胞毒性受体多克隆抗体制备与鉴定. 中国兽医学报. 2021. 41(11): 2141-2147+2154.
五、联系方式
地址：陕西省咸阳市杨陵示范区西农路22号西北农林科技大学动物医学院
邮编：712100
邮箱：dewey3600@nwsuaf.edu.cn。