萧 飒
一、个人基本信息
姓名: 萧飒；学位：博士；
职称：教授； 指导教师资格：博士生导师。
二、求学经历
1986-1990年北京农学院 学士
1992-1993年中国科学院研究生院在职研究生基础课学习
1996-2001年日本京都大学 博士
三、工作经历
1990-1996年 中国科学院遗传研究所，实习研究员
2002-2006年 美国纽约西奈山医学院，博士后
2007-2013年 美国马里兰大学兽医学院，研究助理
2013.09-至今 西北农林科技大学动物医学院，教授
四、研究方向
1. 新城疫病毒及其他禽副粘病毒的遗传学特性及流行病学。
2. 新城疫病毒的分子致病机制。
3. 病毒的基因转录、复制及与宿主的相互作用。
4. RNA病毒的反向遗传系统、诊断及疫苗的研发。
五、讲授课程
兽医流行病学；兽医传染病学；禽病专题；动物疫病防控专题；动物疫病防控与案例分析；动物疫病防控理论与实践。
六、科研项目
1. 国家自然科学基金面上项目（31572533；31972662），主持
2. 陕西省农业专项-家禽疫病防控技术研发及应用，主持
3. 西北农林科技大学人才引进科研启动资金，主持
七、 发表SCI论文（近年）
1. Zhang Y, Wang W, Li Y, Liu J, Wang W, Bai J, Yang Z, Liu H, Xiao S*. A pigeon paramyxovirus type 1 isolated from racing pigeon as an inactivated vaccine candidate provides effective protection. Poult Sci. 2022;101(10):102097.
2. Zhao X, Zhao H, Zhou Z, Miao Y, Li R, Yang B, Cao C, Xiao S, Wang X, Liu H, Wang J, Yang Z. Characterization of Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates That Cause Diarrhea in Sheep in Northwest China. Microbiol Spectr. 2022;10(4):e0159522.
3. Nian X, Li L, Ma X, Li X, Li W, Zhang N, Ohiolei JA, Li L, Dai G, Liu Y, Yan H, Fu B*, Xiao S*, Jia W*. Understanding pathogen-host interplay by expression profiles of lncRNA and mRNA in the liver of Echinococcus multilocularis-infected mice. PLoS Negl Trop Dis. 2022 ;16(5):e0010435.
4. Wang C, Hu R, Duan L, Hou Q, Yang M, Wang T, Liu H, Xiao S, Dang R, Wang J, Wang X, Zhang S, Yang Z. The canonical Wnt/β-catenin signaling pathway facilitates pseudorabies virus proliferation and enhances virus-induced autophagy. Vet Microbiol. 2022; 272: 109502.
5. Han R, Liang L, Qin T, Xiao S*, Liang R*. Encephalomyocarditis Virus 2A Protein Inhibited Apoptosis by Interaction with Annexin A2 through JNK/c-Jun Pathway. Viruses. 2022 Feb 9;14(2):359.
6. Wang C, Wang T, Duan L, Chen H, Hu R, Wang X, Jia Y, Chu Z, Liu H, Wang X, Zhang S, Xiao S, Wang J, Dang R, Yang Z. Evasion of Host Antiviral Innate Immunity by Paramyxovirus Accessory Proteins. Front Microbiol. 2022 Jan 31;12:790191.
7. Chen X, Jia Y, Wei N, Ye C, Hao H, Xiao S, Wang X, Liu H, Yang Z. Identification of a new amino acid mutation in the HN protein of NDV involved in pathogenicity. Vet Res. 2021 Dec 20;52(1):147.
8. Li Y, Jia D, Wang J, Li H, Yin X, Liu J, Wang J, Guan G, Luo J, Yin H, Xiao S, Li Y. Probiotics Isolated From Animals in Northwest China Improve the Intestinal Performance of Mice. Front Vet Sci. 2021 Sep 27;8:750895.
9. Tong L, Chu Z, Gao X, Yang M, Adam FEA, Theodore DWP, Liu H, Wang X, Xiao S, Yang Z. Newcastle disease virus V protein interacts with hnRNP H1 to promote viral replication. Vet Microbiol. 2021 Sep;260:109093.
10. Yang M, Ma J, Chu Z, Cao X, Lu K, Shi X, Tong L, Yan C, Liu H, Wang X, Xiao S, Yang Z. Musashi1 inhibit the release of Newcastle disease viruses through preventing apoptosis of DF-1 cells. Poult Sci. 2021 Jul;100(7):101105.
11. Wang W, Wei Q, Hao Q, Zhang Y, Li Y, Bi Y, Jin Z, Liu H, Liu X, Yang Z*, Xiao S*. Cellular CARD11 Inhibits the Fusogenic Activity of Newcastle Disease Virus via CBM Signalosome-Mediated Furin Reduction in Chicken Fibroblasts. Front Microbiol. 2021 Feb 2;12:607451.
12. Chen X, Chen S, Chen H, Tian J, Zhao X, Jia Y, Xiao S, Wang X, Liu H, Yang Z. Comparative biology of two genetically closely related Newcastle disease virus strains with strongly contrasting pathogenicity. Vet Microbiol. 2021 Feb;253:108977.
13. Jin Z, Wei Q, Bi Y, Li Y, Huo N, Mou S, Wang W, Liu H, Yang Z, Chen H*, Xiao S*. Identification of a potential neutralizing linear epitope of hemagglutinin-neuraminidase in Newcastle disease virus. Virol J. 2021 Jan 6;18(1):8.
14. Yan C, Liu H, Jia Y, Prince-Theodore DW, Yang M, Addoma Adam FE, Ren J, Cao X, Wang X, Xiao S, Zhang S, Yang Z. Screening and mechanistic study of key sites of the hemagglutinin-neuraminidase protein related to the virulence of Newcastle disease virus. Poult Sci. 2020 Jul;99(7):3374-3384.
15. Liu WG, Luo J, Ren QY, Qu ZQ, Lin HL, Xu XF, Ni J, Xiao RH, Chen RG, Rashid M, Wu ZG, Tan YC, Qiu XF, Luo JX, Yin H, Wang H, Yang ZQ, Xiao S, Liu GY. A Novel miRNA-hlo-miR-2-Serves as a Regulatory Factor That Controls Molting Events by Targeting CPR1 in Haemaphysalis longicornis Nymphs. Front Microbiol. 2020 May 29;11:1098.
16. WangX, Jia Y, Ren J, Liu H, Xiao S, Wang X, Yang Z. MicroRNA gga-miR-455-5p Suppresses Newcastle Disease Virus Replication via Targeting Cellular Suppressors of Cytokine Signaling 3. Vet Microbiol, 2019, 239:108460.
17. Wang X, JiaY, Ren J, Huo N, Liu H, Xiao S, Wang X, YangZ. Newcastle Disease Virus Nonstructural V Protein Upregulates SOCS3 Expression to Facilitate Viral Replication Depending on the MEK/ERK Pathway. Front Cell Infect Microbiol , 2019, 9: 317.
18. Wang W, Chang X, Yao W, Wei N, Huo N, Wang Y, Wei Q, Liu H, Wang X, Zhang S, *Yang Z, *XiaoS. Host CARD11 inhibits Newcastle disease virus replication by suppressing viral polymerase activity in neurons. J. Virol. 2019 Sep; doi:10.1128/ JVI.01499-19
19. Bi Y, Jin Z, Wang Y, Mou S, Wang W, Wei Q, Huo N, Liu S, Wang X, Yang Z, *Chen H, *Xiao S. Identification of Two Distinct Linear B Cell Epitopes of the Matrix Protein of the Newcastle Disease Virus Vaccine Strain LaSota. Viral Immunol . 2019 Jun; 32(5): 221-229.
20. Chu Z, Gao X, Liu H, Ma J, Wang C, Lu K, Han Q, Wang Y, Wang C, Adam FEA, Wang X, Xiao S, *Yang Z. Newcastle disease virus selectively infects dividing cells and promotes viral proliferation. Vet Res . 2019 Apr 18;50(1):27.
21. Wang X, Jia Y, Wang X, Wang C, Lv C, Li X, Chu Z, Han Q, Xiao S, Zhang S, *Yang Z. MiR-375 Has Contrasting Effects on Newcastle Disease Virus Growth Depending on the Target Gene. Int J Biol Sci. 2019 Jan 1;15(1):44-57.
22. Li X, Jia Y, Liu H, Wang X, Chu Z, Hu R, Ren J, Xiao S, Zhang S, Wang X, *Yang Z. High level expression of ISG12(1) promotes cell apoptosis via mitochondrial-dependent pathway and so as to hinder Newcastle disease virus replication. Vet Microbiol. 2019 Jan;228:147-156.
23. Wang C, Chu Z, Liu W, Pang Y, Gao X, Tang Q, Ma J, Lu K, Adam FEA, Dang R, Xiao S, Wang X, *Yang Z. Newcastle disease virus V protein inhibits apoptosis in DF-1 cells by downregulating TXNL1. Vet Res . 2018 Oct 5;49(1):102.
24. Chu Z, Wang C, Tang Q, Shi X, Gao X, Ma J, Lu K, Han Q, Jia Y, Wang X, Adam FEA, Liu H, Xiao S, Wang X, *Yang Z. Newcastle Disease Virus V Protein Inhibits Cell Apoptosis and Promotes Viral Replication by Targeting CacyBP/SIP. Front Cell Infect Microbiol . 2018 Sep 3;8:304.
25. Chu Z, Ma J, Wang C, Lu K, Li X, Liu H, Wang X, Xiao S, *Yang Z. Newcastle Disease Virus V Protein Promotes Viral Replication in HeLa Cells through the Activation of MEK/ERK Signaling. Viruses . 2018 Sep 12;10(9).
26. Guo Y, Zhao J, Chang X, Yao W, Wang H, Wang W, Wang X, Zhang S, Yang Z, *Xiao S. α2,3- and α2,6-linked sialic acids are important for cell binding and replication of Newcastle disease virus in chicken primary neuronal cells. Acta Virol . 2018; 62(3): 235-245.
27. Jia YQ, Wang XL, Wang XW, Yan CQ, Lv CJ, Li XQ, Chu ZL, Adam FEA, Xiao S, Zhang SX, *Yang ZQ. Common microRNA⁻mRNA Interactions in Different Newcastle Disease Virus-Infected Chicken Embryonic Visceral Tissues. Int J Mol Sci . 2018 Apr 25;19(5).
八、联系方式
通信地址：陕西，杨凌，西农路22号，邮编712100。
电子邮箱：saxiao@nwafu.edu.cn