齐雪峰

作者:  来源:  发布日期:2019-05-07 浏览次数:

 一、个人基本信息

  齐雪峰,男

  学科专业:预防兽医学       

  出生日期:1977.03

  学位:博士

  职称:教授

  职级:四级

  指导教师资格:博士生导师

  研究方向:兽医微生物与免疫学,羊类疫病致病与免疫机制

  现任职务:教师

  开设课程:本科生:《兽医生物制品学》;研究生《兽医生物制品研制与应用》

 二、教育经历(从大学本科开始,按时间倒排序):

  2005/09 - 2008/06毕业于四川农业大学动物医学院预防兽医学专业,获得博士学位;

  2002/09 - 2005/06毕业西南民族大学生命科学与技术学院预防兽医学专业,获得硕士学位;

  1997/09 - 2001/06毕业于西南民族大学生命科学与技术学院动物医学,获得学士学位。

  三、工作经历(科研与学术工作经历,按时间倒排序):

  2019/01 - 至今,任职于西北农林科技大学动物医学学院,教授;

  2012/01 - 2018/12,任职于西北农林科技大学动物医学学院,副教授;

  2013/08 - 2014/09,在普渡大学(Purdue University)生物科学学院,访问学者;

  2008/06 - 2011/12任职于西北农林科技大学动物医学学院,讲师。

 四、近年发表的代表性论著:

  [1] Qi XF, Wang T, Xue Q, Li Z, Yang B, Wang J. MicroRNA expression profiling of goat peripheral blood mononuclear cells in response to peste des petits ruminants virus infection. Veterinary Research 2018, 49:62.

  [2] Yang B, Qi XF (Co-first author), Chen Z, Chen S, Xue Q, Jia P, Wang T, Wang J. Binding and entry of peste des petits ruminants virus into caprine endometrial epithelial cells profoundly affect early cellular gene expression. Veterinary Research 2018, 49:8.

  [3] Wang X, Qi XF (Co-first author), Yang B, Chen S, Wang J. Autophagy Benefits the Replication of Egg Drop Syndrome Virus in Duck Embryo Fibroblasts. Frontiers in Microbiology 2018, 9:1091.

  [4] Qi XF, Qin L, Du R, Chen Y, Lei M, Deng M, Wang J*. Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation. Frontiers in Cellular and Infection Microbiology 2017, 7:315.

  [5] Qi XF, Zhang H, Wang Q, Wang J*. Down-regulation of cellular protein heme oxygenase-1 inhibits proliferation of avian influenza virus H9N2 in chicken oviduct epithelial cells. Journal of General Virology 2017, 99:36-43.

  [6] Qi XF, Xu J, Wang Z, Wang X, Wang J*. The role of hexon in egg drop syndrome virus (EDSV) inducing apoptosis in duck embryo fibroblast cells. Research in Veterinary Science 2017,114:395-400.

  [7] Qi XF, Liu C, Li R, Zhang H, Xu X, Wang J*. Modulation of the innate immune-related genes expression in H9N2 avian influenza virus-infected chicken macrophage-like cells (HD11) in response to Escherichia coli LPS stimulation. Research in Veterinary Science 2017, 111:36-42

  [8] Qi XF, Tan D, Wu C, Tang C, Li T, Han X, Wang J, Liu C, Li R, Wang J*. Deterioration of eggshell quality in laying hens experimentally infected with H9N2 avian influenza virus. Veterinary Research 2016, 47:35.

  [9] Qi XF, Lei M, Qin L, Xie M, Zhao D, Wang J*. Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss. Immunology 2016, 148:70-82.

  [10] Qi XF, Zhang H, Wang Q, Wang J* The NS1 protein of avian influenza virus H9N2 induces oxidative-stress-mediated chicken oviduct epithelial cells apoptosis. Journal of General Virology 2016, 97:3183-3192.

  [11] Mingzhu Lei, Lijuan Qin, Aihua Wang, Yaping Jin, Xianjun Zhao, Xuefeng Qi*. Fn14 receptor appears as a modulator of ovarian steroid-related regulation of goat endometrial epithelial cell IL-18 expression. American Journal of Reproductive Immunology 2015,73(5):428-436.

   [12] Lijuan Qin, Mingzhu Lei, Dandan Zhao, Aihua Wang, Yaping Jin, Xuefeng Qi*. Goat uterine DBA+ leukocytes differentiation and cytokines expression respond differently to cloned versus fertilized embryos. PLoS One 2015,10(1):e0116649.

   [13] Mingzhu Lei, Lijuan Qin, Dandan Zhao, Aihua Wang, Xianjun Zhao, Yaping Jin, Xuefeng Qi*. Tumor necrosis factor-like weak inducer of apoptosis regulates the phenotype and cytotoxic activity of goat uterine natural killer cells. Journal of Animal Science 2015,93(2):589-597.

  [14] Xuefeng Qi, Zhichun Nan, Yaping Jin, Yanyan Qu, Xianjun Zhao, Aihua Wang. Stromal-epithelial interactions modulate the effect of ovarian steroids on goat uterine epithelial cell interleukin-18 release. Domestical Animal Endocrinology 2012;42:210-9.

  [15] Xuefeng Qi, Yanyan Qu, Zhichun Yaping Jin, Xianjun Zhao, Aihua Wang. Caprine endometrial stromal cells modulate the effects of steroid hormones on cytokine secretion by endometrial epithelial cells in vitro. Reproductive Biology 2012;12:309-15.

  [16] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y., Luo, Q.H., Chen, X.Y. Intestinal mucosal immune response against virulent duck enteritis virus infection in ducklings. Research in Veterinary Science 2009, 87(2):218-225.

  [17] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Guo, Y.F., Jia, R.Y. Replication kinetics of duck virus enteritis vaccine virus in ducklings immunized by the mucosal or systemic route using real-time quantitative PCR. Research in Veterinary Science 2009, 86(1):63-67.

  [18] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y. The pathogenesis of duck virus enteritis in experimentally infected ducks: a quantitative time-course study using TaqMan PCR. Avian Pathology 2008,37(3):307-310.

  [19] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y. Quantitative analysis of virulent duck enteritis virus loads in experimentally infected ducklings. Avian Diseases 2008, 52(2):338-344.

  [20] Yang XY, Qi XF (Co-first author), Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y., Chen, X.Y. Intestinal mucosal immune response in ducklings following oral immunisation with an attenuated duck enteritis virus vaccine. Veterinary Journal 2010, 185(2):199-203.

  [21] Qi, X.F., Bai, D.N, Zhao, X.J., Wang, A.H. Probiotic activities of lab in endometritis: Probiotic activities of three Lactic acid bacteria strains isolated from healthy bovine cervix: in vitro adherence to immortalized endometrial epithelial cells and antimicrobial properties. Journal of Animal and Veterinary Advances 2011, 10(4):484-488.

  [22] Qi, X.F., Jin, Y.P., Liu, H.M., Wang, A.H., Zhzo, X.J. Microencapsulation of Lactobacillus brevis and preliminary evaluation of their therapeutic effect on the diarrhea of neonatal calf. Journal of Animal and Veterinary Advances 2011, 10(2):151-156.

  [23] Qi, X.F., Wang, F., Wang, D.H., Wang, A.H., Wang, A.H., Wang, C.J., Yang, J.L., Zhao, B., Zhzo, X.J. Effect of enterotoxin on promotion of adhesion of enterotoxigenic Escherichia coli. Journal of Food, Agriculture & Environment 2011, 9(3-4):576-579.

  [24] Qi, X.F., Huang, N., Zhao, B., Wang, C.J., Zhzo, X.J. Prevalence serogroup and genotypes for fimbriae and enterotoxins in Escherichia coli isolated from diarrheic piglets in western China. Journal of Swine Health and Production 2012, 20(2):290-293.

  五、科研项目:

  国家自然科学基金面上项目,31572588、TWEAK对山羊uNK细胞分化和功能的调节作用及其机制、2016/01-2019/12、64万元、在研、主持。

  陕西省重点研发项目(一般项目),S2018-ZDYF-YBXM-NY-0003、奶山羊繁殖障碍疫病的综合防治技术研究与集成示范、2018/01-2019/12、15万元、在研、主持。

  教育部留学回国科研项目,TWEAK/IL-18对山羊uNK细胞分泌调节机制、2016/01-2017/12、2.6万元、结题、主持。

  教育部直属高校科研基本业务费重点项目,NF-κB信号通路介导uNK细胞对子宫内膜容受性的作用及分子机制研究、2013/01-2016/12、20万、结题、主持。

  国家自然科学基金青年项目,30901089、山羊胚胎与子宫内膜细胞对uNK细胞活化和分泌表达的影响、2010/01-2012/12、20万元、结题、主持。

  教育部高等学校博士学科点青年教师科研专项,20090204120011、山羊胚胎与子宫内膜细胞对CD4+CD25+Tr细胞活化和分泌表达的影响、2010/01-2012/12、3.6万元、结题、主持。

  西北农林科技大学“青年学术骨干支持计划”、2010/01-2012/12、20万元、结题、主持。

 六、社会兼职:中国微生物学会终身会员;中国免疫学会会员。担任《病毒学报》、《畜牧兽医学报》、《Veterinary Research》、《Frontiers in microbiology》等杂志的函评专家。

 七、联系方式:陕西省杨凌西北农林科技大学动物医学院,邮编:712100;电子邮箱:yxyan2002@163.com

  

  

  


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