雒昂

一、个人基本信息

雒昂，男，1985年10月，陕西咸阳，博士，讲师。

二、教育和研究经历

教育经历：

2007年7月毕业于青海大学农牧学院动物医学系食品卫生检验专业，获得学士学位；2011年7月毕业于南开大学生命科学学院遗传学专业，获得硕士学位；2016年7月毕业于南开大学生命科学学院遗传学专业，获得博士学位。

研究经历：

2016年9月至2020年7月，美国明尼苏达大学双城分校生物化学与分子生物学系博士后。

2020年8月至今，西北农林科技大学动物医学院基础兽医学系讲师。

三、研究方向及开设课程

研究方向：动物模型和疾病机理；开设课程：本科生动物生理学。

四、代表性学术成果

1. Ang Luo, Yao Gong, Hyungjin Kim, Yue Chen. Proteome Dynamics Analysis Identified Metabolic-Sensing DNA Damage Response in Prostate Cancer Cells. NAR Cancer, Volume 2, Issue 2, June 2020, https://doi.org/10.1093/narcan/zcaa010.

2. Ang Luo, Yue Chen. Label-free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2. Journal of Proteome Research.J. Proteome Res. 2020, 19, 260−268.

3. Luke N Erber, Ang Luo, and Yue Chen. Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation. Molecular & Cellular Proteomics. 2019 Jun 25. doi: 10.1074/mcp.RA119.001535.

4. Yunan Li, Ang Luo, Luke Erber, and Yue Chen. Quantifying Ubiquitination Signaling with a Chemical Proteomics Strategy. The FASEB Journal 33 (1_supplement), lb245-lb245

5. Yunan Li, Jonathan Evers, Ang Luo, Luke Erber, Zachary Postler, Yue Chen. A Quantitative Chemical Proteomics Approach for Site‐specific Stoichiometry Analysis of Ubiquitination. Angew Chem Int Ed Engl. 2019 Jan ;58(2):537-541.

6. Ang Luo, Kailun Zhang, Yanxia Zhao, Zhengmao Zhu, Liya Fu, Jintang Dong.

ZNF121 interacts with ZBRK1 and BRCA1 and regulates the expression of their common targets. FEBS Bio Open. 2018 Dec; 8(12): 1943–1952.

7. Leilei Qi, Baotong Zhang, Shiying Zhang, Xinpei Ci, Qiao Wu, Gui Ma, Ang Luo, Liya Fu, Jamie L. King, Rita Nahta, and Jin-Tang Dong. ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression. Oncotarget. 2017 May 30; 8(22): 36054–36066.

8. Ang Luo, Xuan Zhang, Liya Fu, Zhengmao Zhu, Jintang Dong. Zinc finger factor ZNF121 is a MYC-interacting protein functionally affecting MYC and cell proliferation in epithelial cells. Journal of Genetics and Genomics. 2016, 43(12): 677-685.

9. Ang Luo, Dan Su, Xuan Zhang, Leilei Qi, Liya Fu, Jintang Dong. Estrogen-estrogen receptor signaling suppresses the transcription of ERRF in breast cancer cells. Journal of Genetics and Genomics. 2016, 43(9): 565-7.

10.  Ang Luo, Xuan Zhang. ERRF is essential for Estrogen-Estrogen Receptor alpha signaling pathway in ER positive breast cancer cells. Biochem Biophys Res Commun. 2016 May 27;474(2):400-405.

五、联系方式

西北农林科技大学北校区生命科学大型仪器共享中心2-B-22房间。电子邮箱：luoang369@uwafu.edu.cn.